close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV64496.1TatD-related deoxyribonuclease; COGs: COG1831 metal-dependent hydrolase (urease superfamily); InterPro IPR001130; KEGG: dka:DKAM_1464 TatD-related deoxyribonuclease; PFAM: TatD-related deoxyribonuclease; SPTR: TatD-related deoxyribonuclease; PFAM: TatD related DNase. (281 aa)    
Predicted Functional Partners:
ADV64497.1
KEGG: tag:Tagg_1058 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: HIT zinc finger.
       0.633
ADV64498.1
AIR synthase related protein domain protein; COGs: COG0309 Hydrogenase maturation factor; InterPro IPR011854: IPR000728: IPR010918; KEGG: dka:DKAM_1463 AIR synthase related protein domain protein; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; SPTR: AIR synthase related protein domain protein; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain.
       0.548
ADV64799.1
Radical SAM domain protein; COGs: COG1031 Fe-S oxidoreductase; InterPro IPR006638: IPR007197; KEGG: dka:DKAM_0650 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily.
  
     0.542
ADV64495.1
COGs: COG4721 membrane protein; InterPro IPR017195; KEGG: dka:DKAM_1465 ABC transporter, permease protein; PFAM: ABC-type thiamin-related transport system, permease component 1, predicted; SPTR: ABC transporter, permease protein; PFAM: ABC-type cobalt transport system, permease component.
       0.534
ADV64499.1
KEGG: dka:DKAM_1462 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.512
ADV65402.1
NMD3 family protein; COGs: COG1499 NMD protein affecting ribosome stability and mRNA decay; InterPro IPR007064; KEGG: dka:DKAM_1085 NMD protein affecting ribosome stability and mRNA decay-like protein; PFAM: NMD3 family protein; SPTR: NMD protein affecting ribosome stability and mRNA decay-like protein; PFAM: NMD3 family.
 
     0.467
cmk
COGs: COG1102 Cytidylate kinase; InterPro IPR011892: IPR003959; KEGG: dka:DKAM_1149 cytidylate kinase; PFAM: AAA ATPase central domain protein; SPTR: Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Adenylate kinase; TIGRFAM: cytidylate kinase, putative.
 
     0.444
ADV65048.1
Pantothenate synthetase; COGs: COG1701 conserved hypothetical protein; InterPro IPR002855; KEGG: dka:DKAM_0336 hypothetical protein; PFAM: protein of unknown function DUF137; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF137.
 
     0.434
ADV65168.1
Transcriptional regulator, XRE family; COGs: COG1395 transcriptional regulator protein; InterPro IPR020886: IPR001387; KEGG: dka:DKAM_0813 predicted transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Predicted transcriptional regulator; PFAM: Helix-turn-helix.
  
     0.411
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
Server load: low (38%) [HD]