close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV64511.1COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterPro IPR002129; KEGG: dka:DKAM_0021 pyridoxal-dependent decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; SPTR: Pyridoxal-dependent decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain; TIGRFAM: tyrosine decarboxylase MnfA. (381 aa)    
Predicted Functional Partners:
ADV64324.1
COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: dka:DKAM_1380 pyridoxal phosphate-dependent aminotransferase; PFAM: aminotransferase class-III; SPTR: Pyridoxal phosphate-dependent aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.941
ADV64623.1
Acetylornithine transaminase; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: dka:DKAM_0124 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.941
ADV64851.1
COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: pab:PAB0086 pyridoxal phosphate-dependent aminotransferase; PFAM: aminotransferase class-III; SPTR: Pyridoxal phosphate-dependent aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.941
ADV65033.1
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838: IPR004839: IPR001176; KEGG: dka:DKAM_0468 aspartate aminotransferase (AspC), conjectural; PFAM: aminotransferase class I and II; SPTR: Aspartate aminotransferase (AspC), conjectural; PFAM: Aminotransferase class I and II.
  
 
 0.940
ADV65048.1
Pantothenate synthetase; COGs: COG1701 conserved hypothetical protein; InterPro IPR002855; KEGG: dka:DKAM_0336 hypothetical protein; PFAM: protein of unknown function DUF137; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF137.
 
  
 0.939
ADV64512.1
COGs: COG0478 RIO-like serine/threonine protein kinase fused to N-terminal HTH domain; InterProIPR008266: IPR018935: IPR000687: IPR015285: IPR 018934; KEGG: dka:DKAM_0022 RIO-like serine/threonine kinase; PFAM: RIO-like kinase; RIO2 kinase, winged helix domain protein; PRIAM: Non-specific serine/threonine protein kinase; SMART: protein of unknown function RIO1; SPTR: RIO-like serine/threonine kinase; PFAM: RIO1 family; Rio2, N-terminal.
 
     0.906
ADV64510.1
COGs: COG1224 DNA helicase TIP49 TBP-interacting protein; InterPro IPR003593: IPR003959: IPR010339; KEGG: dka:DKAM_0020 TatA binding protein (TBP)-interacting protein (TIP49-like); PFAM: TIP49 domain-containing protein; AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: TATA binding protein (TBP)-interacting protein (TIP49-like); PFAM: TIP49 C-terminus.
 
     0.852
ADV64902.1
Asparaginase; COGs: COG1446 Asparaginase; InterPro IPR000246; KEGG: dka:DKAM_0544 asparaginase; PFAM: peptidase T2 asparaginase 2; SPTR: Asparaginase; PFAM: Asparaginase.
    
 0.835
pyrB
COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR002082: IPR006130: IPR006132: IPR006131; KEGG: dka:DKAM_0742 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase.
    
  0.803
ADV64513.1
Protein of unknown function DUF460; COGs: COG2433 conserved hypothetical protein; InterPro IPR007408; KEGG: dka:DKAM_0023 DUF460 domain containing protein; PFAM: protein of unknown function DUF460; SPTR: DUF460 domain containing protein; PFAM: Protein of unknown function (DUF460).
 
     0.602
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.