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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nucSProtein of unknown function DUF91; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family. (277 aa)    
Predicted Functional Partners:
ADV64520.1
Methyltransferase type 11; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: dka:DKAM_0095 putative methyltransferase; PFAM: Methyltransferase type 11; SPTR: Putative methyltransferase; PFAM: Methyltransferase domain.
       0.876
ADV64517.1
Protein of unknown function DUF431; COGs: COG2428 conserved hypothetical protein; InterPro IPR007364; KEGG: dka:DKAM_0027 protein of unknown function DUF431; PFAM: protein of unknown function DUF431; SPTR: Putative uncharacterized protein; PFAM: Predicted SAM-dependent RNA methyltransferase.
 
     0.842
ADV64518.1
Hypothetical protein; COGs: COG4900 metallopeptidase; KEGG: ape:APE_1561 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
ADV64521.1
Small nuclear ribonucleoprotein, LSM family; COGs: COG1958 Small nuclear ribonucleoprotein (snRNP) homolog; InterPro IPR006649: IPR001163; KEGG: dka:DKAM_0094 small nuclear ribonucleoprotein, LSM family; PFAM: Like-Sm ribonucleoprotein core; SMART: Sm-family ribonucleoprotein; SPTR: Small nuclear ribonucleoprotein, LSM family; PFAM: LSM domain.
       0.695
pcn
Proliferating cell nuclear antigen PcnA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
 
 
 
 0.485
radA
DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
     
 0.484
ADV64516.1
KEGG: dka:DKAM_0026 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.482
rfcL
Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily.
  
 
 
 0.474
ADV64515.1
Protein of unknown function DUF814; COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616: IPR008532; KEGG: dka:DKAM_0025 protein of unknown function DUF814; PFAM: protein of unknown function DUF814; Fibronectin-binding A domain protein; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA).
       0.466
fau-1
Protein of unknown function DUF402; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.
  
     0.422
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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