close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV64543.1Transposase, IS605 OrfB family; COGs: COG0675 Transposase and inactivated derivatives; InterPro IPR010095; KEGG: pcl:Pcal_0427 IS605 family transposase OrfB; PFAM: transposase IS605 OrfB; SPTR: Transposase, IS605 OrfB family; TIGRFAM: transposase, IS605 OrfB family; PFAM: Putative transposase DNA-binding domain; Probable transposase; TIGRFAM: transposase, IS605 OrfB family, central region. (444 aa)    
Predicted Functional Partners:
ADV64978.1
Transposase; COGs: COG0675 Transposase and inactivated derivatives; InterPro IPR010095; KEGG: sid:M164_0600 transposase, IS605 OrfB family; PFAM: transposase IS605 OrfB; SPTR: Transposase, IS605 OrfB family; TIGRFAM: transposase, IS605 OrfB family; PFAM: Putative transposase DNA-binding domain; Probable transposase; TIGRFAM: transposase, IS605 OrfB family, central region.
  
     0.617
ADV64544.1
COGs: COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related protein; InterPro IPR001950: IPR017228; KEGG: dka:DKAM_0055 translation initiation factor SUI1; PFAM: translation initiation factor SUI1; SPTR: Translation initiation factor 1 (EIF-1/SUI1); PFAM: Translation initiation factor SUI1; TIGRFAM: translation initation factor SUI1, putative, prokaryotic; Belongs to the SUI1 family.
       0.558
ADV65433.1
DNA binding domain protein, excisionase family; COGs: COG2452 site-specific integrase-resolvase; InterPro IPR006118: IPR010093: IPR000551: IPR006119; KEGG: dka:DKAM_1473 IS element ISDka1 orfA, putative resolvase; PFAM: Resolvase domain; regulatory protein MerR; SPTR: IS element ISDka1 orfA, putative resolvase; TIGRFAM: DNA binding domain protein, excisionase family; PFAM: Resolvase, N terminal domain; TIGRFAM: DNA binding domain, excisionase family.
 
  
 0.468
Pullulanase
Pullulanase; COGs: COG1449 Alpha-amylase/alpha-mannosidase; InterPro IPR004300: IPR019248; KEGG: dka:DKAM_0979 pullulanase, glycoside hydrolase, family 57; PFAM: glycoside hydrolase family 57; Protein of unknown function DUF2223; SPTR: Pullulanase, glycoside hydrolase, family 57; PFAM: Domain of unknown function (DUF2223); Glycosyl hydrolase family 57.
 
     0.411
ADV64545.1
KEGG: dka:DKAM_0054 DNA-directed RNA polymerase subunit P; SPTR: DNA-directed RNA polymerase subunit P.
       0.409
ADV65188.1
Cation diffusion facilitator family transporter; COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: dka:DKAM_0834 cation efflux system protein; PFAM: cation efflux protein; SPTR: Cation efflux system protein; TIGRFAM: cation diffusion facilitator family transporter; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter.
 
     0.402
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
Server load: low (22%) [HD]