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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV64591.1Cytidyltransferase-related domain protein; COGs: COG1056 Nicotinamide mononucleotide adenylyltransferase; InterPro IPR004821: IPR004820; KEGG: dka:DKAM_0759 cytidyltransferase-related domain protein; PFAM: cytidylyltransferase; PRIAM: Nicotinamide-nucleotide adenylyltransferase; SPTR: Cytidyltransferase-related domain protein; TIGRFAM: cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain. (182 aa)    
Predicted Functional Partners:
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
 
  
 0.941
ADV65196.1
COGs: COG1488 Nicotinic acid phosphoribosyltransferase; InterPro IPR007229: IPR002638; KEGG: dka:DKAM_0842 nicotinate phosphoribosyltransferase; PFAM: Quinolinate phosphoribosyl transferase; PRIAM: Nicotinate phosphoribosyltransferase; SPTR: Quinolinate phosphoribosyl transferase; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: putative nicotinate phosphoribosyltransferase.
    
 0.930
ADV65381.1
COGs: COG0061 sugar kinase; InterPro IPR002504; KEGG: dka:DKAM_1065 probable inorganic polyphosphate/ATP-NAD kinase; PFAM: ATP-NAD/AcoX kinase; SPTR: Probable inorganic polyphosphate/ATP-NAD kinase; PFAM: ATP-NAD kinase.
    
 0.919
ADV65568.1
Cytidyltransferase-related domain protein; COGs: COG1056 Nicotinamide mononucleotide adenylyltransferase; InterPro IPR004820: IPR001980: IPR004821; KEGG: dka:DKAM_1286 nicotinamide-nucleotide adenylyltransferase; PFAM: cytidylyltransferase; SPTR: Nicotinamide-nucleotide adenylyltransferase; TIGRFAM: cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain.
  
  
 
0.909
ADV64589.1
COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004408: IPR004143: IPR003142; KEGG: dka:DKAM_0757 biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin protein ligase domain protein; SPTR: Biotin--acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: Biotin protein ligase C terminal domain; Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region.
     
 0.881
ADV64590.1
Protein of unknown function UPF0153; InterPro IPR005358; KEGG: dka:DKAM_0758 UPF0153 domain containing protein; PFAM: protein of unknown function UPF0153; SPTR: UPF0153 domain containing protein; PFAM: Uncharacterised protein family (UPF0153).
       0.875
ADV64595.1
Metal dependent phosphohydrolase; COGs: COG1078 HD superfamily phosphohydrolase; InterPro IPR003607: IPR006674; KEGG: dka:DKAM_0765 metal-dependent phosphohydrolase, HD region; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal-dependent phosphohydrolase, HD region; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative.
  
    0.570
ADV65595.1
KEGG: dka:DKAM_1310 putative transcriptional regulator, CopG/Arc/MetJ family; SPTR: Putative transcriptional regulator, CopG/Arc/MetJ family; PFAM: Ribbon-helix-helix protein, copG family.
  
    0.538
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
  
     0.519
ADV64592.1
KEGG: dka:DKAM_0768 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.510
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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