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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV64610.1AMP phosphorylase; COGs: COG0213 Thymidine phosphorylase; InterProIPR017872: IPR013466: IPR017713: IPR017459: IPR 000312: IPR013102; KEGG: dka:DKAM_0158 AMP phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like; glycosyl transferase family 3; PRIAM: Thymidine phosphorylase; SPTR: AMP phosphorylase; TIGRFAM: AMP phosphorylase; thymidine phosphorylase; PFAM: Glycosyl transferase family, a/b domain; Pyrimidine nucleoside phosphorylase C-terminal domain; Cell division protein 48 (CDC48), N-terminal domain; Glycosyl transferase family, helical [...] (509 aa)    
Predicted Functional Partners:
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
  
 
 0.841
ADV65021.1
Ribose 1,5-bisphosphate isomerase; COGs: COG1184 Translation initiation factor 2B subunit eIF-2B alpha/beta/delta family; InterPro IPR011559: IPR005250: IPR000649; KEGG: dka:DKAM_0459 translation initiation factor IF-2B subunit delta; PFAM: initiation factor 2B related; PRIAM: S-methyl-5-thioribose-1-phosphate isomerase; SPTR: Putative ribulose-1,5-bisphosphate isomerase; TIGRFAM: translation initiation factor, aIF-2BII family; eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: Initiation factor 2 subunit family; TIGRFAM: eIF-2B alpha/beta/delta-related uncharacterized prot [...]
 
  
 0.693
ADV64670.1
COGs: COG0295 Cytidine deaminase; InterPro IPR016192: IPR006262: IPR002125; KEGG: dka:DKAM_0608 cytidine deaminase; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: Cytidine deaminase; TIGRFAM: cytidine deaminase; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric.
  
  
 0.657
ADV64876.1
COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR017926: IPR006220: IPR011702: IPR004739: IPR 001674: IPR000991; KEGG: dka:DKAM_0479 GMP synthase; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; SPTR: GMP synthase; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase C terminal domain; Glutamine amidotransferase class-I; NAD synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit.
     
 0.623
ADV65601.1
RNA-metabolising metallo-beta-lactamase; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; InterPro IPR011108; KEGG: dka:DKAM_1316 putative exonuclease; PFAM: RNA-metabolising metallo-beta-lactamase; SPTR: Putative exonuclease; PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; Beta-Casp domain.
    0.614
ADV64608.1
Protein of unknown function DUF429; COGs: COG2410 conserved hypothetical protein; KEGG: dka:DKAM_0160 protein of unknown function DUF429; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF429).
       0.584
ADV64609.1
2,3-di-O-geranylgeranylglyceryl phosphate reductase; COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR011777: IPR003042: IPR003953; KEGG: dka:DKAM_0159 geranylgeranyl reductase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: Geranylgeranyl reductase; TIGRFAM: geranylgeranyl reductase; PFAM: Lycopene cyclase protein; TIGRFAM: geranylgeranyl reductase family.
       0.584
ADV65150.1
UspA domain-containing protein; InterPro IPR006016: IPR006015; KEGG: dka:DKAM_0186 UspA domain protein; PFAM: UspA domain-containing protein; SPTR: UspA domain protein; PFAM: Universal stress protein family.
  
    0.584
ADV64771.1
COGs: COG0035 Uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: dka:DKAM_0717 probable uracil phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Probable uracil phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: uracil phosphoribosyltransferase.
  
  
 0.559
ADV65185.1
COGs: COG0035 Uracil phosphoribosyltransferase; KEGG: dka:DKAM_0830 uracil phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: uracil phosphoribosyltransferase.
  
  
 0.559
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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