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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV64699.1Protein of unknown function DUF123; COGs: COG1833 conserved hypothetical protein; InterPro IPR002837; KEGG: dka:DKAM_0664 endonuclease III (nth1); PFAM: protein of unknown function DUF123; SPTR: Endonuclease III (Nth1); PFAM: Domain of unknown function DUF123. (171 aa)    
Predicted Functional Partners:
ADV64698.1
Protein of unknown function DUF296; COGs: COG1661 DNA-binding protein with PD1-like DNA-binding motif; InterPro IPR005175; KEGG: dka:DKAM_0665 DUF296 domain containing protein; PFAM: protein of unknown function DUF296; SPTR: DUF296 domain containing protein; PFAM: Domain of unknown function (DUF296).
       0.830
ADV64700.1
Nucleic acid binding OB-fold tRNA/helicase-type; COGs: COG1599 Single-stranded DNA-binding replication protein A (RPA) large (70 kD) subunit and related ssDNA-binding protein; InterPro IPR004365; KEGG: dka:DKAM_0663 single-stranded DNA-binding protein; PFAM: nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Single-strand DNA-binding protein; manually curated; PFAM: OB-fold nucleic acid binding domain.
       0.734
ADV64701.1
KEGG: dka:DKAM_0662 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Coenzyme PQQ synthesis protein D (PqqD).
       0.730
ADV64696.1
Von Willebrand factor type A; COGs: COG2425 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain; InterPro IPR002035; KEGG: dka:DKAM_0668 hypothetical protein; SMART: von Willebrand factor type A; SPTR: Uncharacterized protein containing a von Willebrand factor type A (VWA) domain; PFAM: VWA domain containing CoxE-like protein.
       0.591
ADV64697.1
ATPase associated with various cellular activities AAA_5; COGs: COG0714 MoxR-like ATPase; InterPro IPR003593: IPR011704; KEGG: dka:DKAM_0667 ATPase associated with various cellular activities, AAA_5; PFAM: ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; SPTR: ATPase associated with various cellular activities, AAA_5; PFAM: AAA domain (dynein-related subfamily).
       0.578
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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