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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV64782.1Protein of unknown function DUF996; COGs: COG2245 membrane protein; InterPro IPR010397; KEGG: dka:DKAM_0701 protein of unknown function (DUF996); PFAM: protein of unknown function DUF996; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF996). (191 aa)    
Predicted Functional Partners:
ADV64781.1
Hypothetical protein; InterPro IPR000601: IPR017441; KEGG: dka:DKAM_0700 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.549
ADV65208.1
InterPro IPR003115; KEGG: dka:DKAM_0858 ParB domain protein nuclease; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: ParB domain protein nuclease; PFAM: ParB-like nuclease domain.
  
     0.527
ADV65296.1
CRISPR-associated autoregulator, DevR family; COGs: COG1857 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR002764: IPR010154; KEGG: mfe:Mefer_1436 CRISPR-associated autoregulator, DevR family; SPTR: CRISPR-associated autoregulator, DevR family; TIGRFAM: CRISPR-associated regulatory protein, Csa2 family; CRISPR-associated autoregulator DevR family; PFAM: CRISPR-associated negative autoregulator DevR/Csa2; TIGRFAM: CRISPR-associated autoregulator DevR family; CRISPR-associated regulatory protein, Csa2 family.
  
     0.491
ADV64773.1
COGs: COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); InterPro IPR000688; KEGG: dka:DKAM_0719 hydrogenase nickel incorporation protein; PFAM: hydrogenase expression/synthesis HypA; SPTR: Probable hydrogenase nickel incorporation protein; PFAM: Hydrogenase expression/synthesis hypA family.
  
     0.422
ADV65596.1
Glycosyl transferase family 39; COGs: COG4346 membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase; InterPro IPR003342; KEGG: dka:DKAM_1312 glycosyl transferase, family 39; PFAM: glycosyl transferase family 39; SPTR: Glycosyl transferase, family 39; PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase.
  
     0.412
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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