close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV64783.1Sigma 54 interacting domain protein; COGs: COG0433 ATPase; InterPro IPR002078; KEGG: dka:DKAM_0704 putative TraG protein; SPTR: Putative TraG protein; PFAM: Domain of unknown function DUF87; Type IV secretion-system coupling protein DNA-binding domain. (633 aa)    
Predicted Functional Partners:
ADV64785.1
Putative TrbE protein; COGs: COG3451 Type IV secretory pathway VirB4 protein; KEGG: dka:DKAM_0706 putative TrbE protein; SPTR: Putative TrbE protein; PFAM: Domain of unknown function DUF87.
 
   
 0.937
ADV64784.1
KEGG: dka:DKAM_0705 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.771
ADV65560.1
KEGG: dka:DKAM_1273 hypothetical protein; SPTR: Putative uncharacterized protein.
 
   
 0.628
ADV64928.1
Protein of unknown function DUF214; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: dka:DKAM_0493 predicted ABC transporter; PFAM: protein of unknown function DUF214; SPTR: Predicted ABC transporter; PFAM: Predicted permease.
 
     0.421
ADV65296.1
CRISPR-associated autoregulator, DevR family; COGs: COG1857 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR002764: IPR010154; KEGG: mfe:Mefer_1436 CRISPR-associated autoregulator, DevR family; SPTR: CRISPR-associated autoregulator, DevR family; TIGRFAM: CRISPR-associated regulatory protein, Csa2 family; CRISPR-associated autoregulator DevR family; PFAM: CRISPR-associated negative autoregulator DevR/Csa2; TIGRFAM: CRISPR-associated autoregulator DevR family; CRISPR-associated regulatory protein, Csa2 family.
  
     0.400
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
Server load: low (26%) [HD]