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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV64799.1Radical SAM domain protein; COGs: COG1031 Fe-S oxidoreductase; InterPro IPR006638: IPR007197; KEGG: dka:DKAM_0650 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily. (527 aa)    
Predicted Functional Partners:
ADV64800.1
Hydrogenase expression/formation protein HypD; COGs: COG0409 Hydrogenase maturation factor; InterPro IPR002780; KEGG: dka:DKAM_0649 hydrogenase formation HypD protein; PFAM: hydrogenase formation HypD protein; SPTR: Hydrogenase formation HypD protein; TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD.
       0.825
ADV64801.1
Molybdenum cofactor cytidylyltransferase; COGs: COG2068 Uncharacterized MobA-related protein; KEGG: dka:DKAM_0648 nucleotidyl transferase; SPTR: Nucleotidyl transferase; PFAM: Uncharacterized protein family UPF0007.
       0.824
ADV64802.1
COGs: COG1392 Phosphate transport regulator (distant homolog of PhoU); InterPro IPR018445; KEGG: dka:DKAM_0647 phosphate transport regulator-like protein; PFAM: Putitive phosphate transport regulator; SPTR: Phosphate transport regulator-like protein; PFAM: Protein of unknown function DUF47; TIGRFAM: conserved hypothetical protein TIGR00153.
       0.724
ADV64496.1
TatD-related deoxyribonuclease; COGs: COG1831 metal-dependent hydrolase (urease superfamily); InterPro IPR001130; KEGG: dka:DKAM_1464 TatD-related deoxyribonuclease; PFAM: TatD-related deoxyribonuclease; SPTR: TatD-related deoxyribonuclease; PFAM: TatD related DNase.
  
     0.542
ADV64803.1
KEGG: dka:DKAM_0646 transcriptional regulator, TrmB; SPTR: Transcriptional regulator, TrmB; PFAM: Sugar-specific transcriptional regulator TrmB.
       0.443
ADV65168.1
Transcriptional regulator, XRE family; COGs: COG1395 transcriptional regulator protein; InterPro IPR020886: IPR001387; KEGG: dka:DKAM_0813 predicted transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Predicted transcriptional regulator; PFAM: Helix-turn-helix.
  
     0.414
priL
DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
 
    0.406
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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