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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnzRNAse Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (249 aa)    
Predicted Functional Partners:
ADV64897.1
RNA methylase; COGs: COG1041 DNA modification methylase; InterPro IPR002296: IPR002052: IPR000241; KEGG: dka:DKAM_0539 putative RNA methylase; PFAM: RNA methylase; SPTR: Putative RNA methylase; PFAM: Putative RNA methylase family UPF0020; TIGRFAM: conserved hypothetical protein TIGR01177.
  
  
 0.904
ADV64898.1
Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR020827: IPR005946: IPR000836; KEGG: dka:DKAM_0540 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase.
  
    0.865
ADV64899.1
Radical SAM domain protein; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR016431: IPR007197; KEGG: dka:DKAM_0541 pyruvate-formate lyase-activating enzyme; PFAM: Radical SAM domain protein; SPTR: Pyruvate-formate lyase-activating enzyme; PFAM: Radical SAM superfamily.
       0.646
ADV64900.1
Protein of unknown function ATP binding protein; COGs: COG1100 GTPase SAR1 and related small G protein; InterPro IPR004130; KEGG: dka:DKAM_0542 GTPase; PFAM: protein of unknown function ATP binding; SPTR: Predicted ATP binding protein; PFAM: Conserved hypothetical ATP binding protein.
       0.642
ADV64876.1
COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR017926: IPR006220: IPR011702: IPR004739: IPR 001674: IPR000991; KEGG: dka:DKAM_0479 GMP synthase; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; SPTR: GMP synthase; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase C terminal domain; Glutamine amidotransferase class-I; NAD synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit.
  
    0.582
ADV64877.1
Pyridoxal-5'-phosphate-dependent protein beta subunit; COGs: COG0498 Threonine synthase; InterPro IPR001926; KEGG: dka:DKAM_0480 pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme.
 
    0.572
rrp41
Ribosomal RNA-processing protein RRP41/SKI6; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
  
  
 0.557
tmcA
Domain of unknown function DUF1726; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
   
    0.551
ADV65593.1
COGs: COG2519 tRNA(1-methyladenosine) methyltransferase and related methyltransferase; InterPro IPR014816; KEGG: dka:DKAM_1308 methyltransferase type 11; PFAM: tRNA methyltransferase complex GCD14 subunit; PRIAM: tRNA (adenine-N(1)-)-methyltransferase; SPTR: Methyltransferase type 11; PFAM: tRNA methyltransferase complex GCD14 subunit.
  
  
 0.503
ADV64469.1
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
     
 0.475
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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