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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV64904.1Glucokinase; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: dka:DKAM_0546 glucokinase (ROK family protein); PFAM: ROK family protein; SPTR: Glucokinase (ROK family protein); PFAM: ROK family; TIGRFAM: ROK family protein (putative glucokinase). (332 aa)    
Predicted Functional Partners:
ADV64387.1
Bifunctional phosphoglucose/phosphomannose isomerase; COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR011857: IPR019490; KEGG: dka:DKAM_1010 bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; PRIAM: Mannose-6-phosphate isomerase; SPTR: Bifunctional phosphoglucose/phosphomannose isomerase; TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bacterial phospho-glucose isomerase C-terminal region; SIS domain; TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase.
 
 
 0.954
ADV64473.1
Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterProIPR016066: IPR005841: IPR005844: IPR005845: IPR 005843; KEGG: dka:DKAM_0012 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase; SPTR: Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-termi [...]
  
 
 0.929
ADV65346.1
Nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: dka:DKAM_1444 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; PFAM: Aldehyde dehydrogenase family.
  
 
 0.905
ADV65219.1
COGs: COG1260 Myo-inositol-1-phosphate synthase; InterPro IPR002587: IPR013021; KEGG: dka:DKAM_0909 myo-inositol-1-phosphate synthase; PFAM: Myo-inositol-1-phosphate synthase; Myo-inositol-1-phosphate synthase GAPDH domain protein; SPTR: Myo-inositol-1-phosphate synthase; PFAM: Myo-inositol-1-phosphate synthase.
     
 0.902
ADV64905.1
COGs: COG0143 Methionyl-tRNA synthetase; InterPro IPR014758: IPR001412: IPR002304: IPR015413; KEGG: dka:DKAM_0547 methionyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); SPTR: Methionyl-tRNA synthetase; TIGRFAM: methionyl-tRNA synthetase; PFAM: Anticodon-binding domain; tRNA synthetases class I (M); TIGRFAM: methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.875
ADV64677.1
COGs: COG1830 DhnA-type fructose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: dka:DKAM_0616 fructose-bisphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Fructose-bisphosphate aldolase; SPTR: Fructose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase.
    
 0.861
fbp
Fructose-bisphosphate aldolase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
    
 0.848
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
    
  0.816
ADV64906.1
Radical SAM domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638: IPR007197; KEGG: dka:DKAM_0548 Fe-S oxidoreductase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Fe-S oxidoreductase; PFAM: Radical SAM superfamily.
       0.729
ADV64676.1
COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002139: IPR002173: IPR011611; KEGG: dka:DKAM_0615 ATP-dependent 6-phosphofructokinase; PFAM: PfkB domain protein; SPTR: ATP-dependent 6-phosphofructokinase; PFAM: pfkB family carbohydrate kinase.
 
  
 0.631
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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