close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV64940.1KEGG: dka:DKAM_0443 hypothetical protein; SPTR: Putative uncharacterized protein. (60 aa)    
Predicted Functional Partners:
ADV64941.1
COGs: COG2248 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR014426; KEGG: dka:DKAM_0442 predicted hydrolase (metallo-beta-lactamase superfamily); SPTR: Predicted hydrolase (Metallo-beta-lactamase superfamily); Belongs to the UPF0282 family.
       0.618
ADV64939.1
KEGG: dka:DKAM_0444 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.613
ADV64938.1
Protein of unknown function DUF58; COGs: COG1721 conserved hypothetical protein (some members contain a von Willebrand factor type A (vWA) domain); InterPro IPR002881; KEGG: dka:DKAM_0445 hypothetical protein; PFAM: protein of unknown function DUF58; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF58.
       0.604
ADV64937.1
ATPase associated with various cellular activities AAA_3; COGs: COG0714 MoxR-like ATPase; InterPro IPR016366: IPR011703: IPR003593; KEGG: dka:DKAM_0446 MoxR-related ATPase, AAA superfamily; PFAM: ATPase associated with various cellular activities AAA_3; SMART: AAA ATPase; SPTR: MoxR-related ATPase, AAA superfamily; PFAM: ATPase family associated with various cellular activities (AAA).
       0.603
ADV64935.1
KEGG: dka:DKAM_0305 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.495
ADV64936.1
KEGG: dka:DKAM_0304 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.495
ADV64942.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1251 NAD(P)H-nitrite reductase; InterPro IPR013027: IPR004099; KEGG: dka:DKAM_0441 NADH:polysulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: NADH:polysulfide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
       0.442
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.