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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fau-1Protein of unknown function DUF402; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences. (475 aa)    
Predicted Functional Partners:
ADV64997.1
Protein of unknown function UPF0147; COGs: COG1698 conserved hypothetical protein; InterPro IPR005354; KEGG: dka:DKAM_0139 hypothetical protein; PFAM: protein of unknown function UPF0147; SPTR: UPF0147 protein DKAM_0139; PFAM: Uncharacterised protein family (UPF0147); Belongs to the UPF0147 family.
       0.851
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.750
flpA
rRNA 2'-O-methyltransferase fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 
 0.721
ADV65039.1
PhoH family protein; COGs: COG1702 Phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR003714: IPR004044: IPR003593: IPR004088; KEGG: dka:DKAM_0327 PhoH family protein; PFAM: PhoH family protein; KH type 2 domain protein; SMART: AAA ATPase; SPTR: PhoH family protein; PFAM: KH domain; PhoH-like protein.
 
    0.578
ADV64998.1
InterPro IPR009563; KEGG: dka:DKAM_0140 hypothetical protein; PFAM: Sjogrens syndrome scleroderma autoantigen 1; SPTR: Uncharacterized Zn-finger containing protein; PFAM: Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27).
       0.554
ADV65164.1
COGs: COG3357 transcriptional regulator protein; KEGG: dka:DKAM_0809 predicted transcriptional regulator consisting of an HTH domain fused to a Zn-ribbon; SPTR: Predicted transcriptional regulator consisting of an HTH domain fused to a Zn-ribbon.
  
     0.467
ADV65055.1
Phosphomethylpyrimidine kinase; COGs: COG1992 conserved hypothetical protein; InterPro IPR019293; KEGG: dka:DKAM_0343 transcriptional regulator, fis family; PFAM: Phosphomethylpyrimidine kinase; SPTR: Transcriptional regulator, Fis family; PFAM: Archaeal phosphomethylpyrimidine kinase.
  
     0.464
tgtA
Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
 
   
 0.460
ADV65615.1
Protein of unknown function DUF54; COGs: COG1325 exosome subunit; InterPro IPR002739; KEGG: dka:DKAM_1330 hypothetical protein; PFAM: protein of unknown function DUF54; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF54.
  
     0.442
ADV64978.1
Transposase; COGs: COG0675 Transposase and inactivated derivatives; InterPro IPR010095; KEGG: sid:M164_0600 transposase, IS605 OrfB family; PFAM: transposase IS605 OrfB; SPTR: Transposase, IS605 OrfB family; TIGRFAM: transposase, IS605 OrfB family; PFAM: Putative transposase DNA-binding domain; Probable transposase; TIGRFAM: transposase, IS605 OrfB family, central region.
  
     0.438
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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