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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65000.1Protein of unknown function DUF126; COGs: COG1786 conserved hypothetical protein; InterPro IPR002840; KEGG: dka:DKAM_0142 putative aconitase, subunit; PFAM: protein of unknown function DUF126; SPTR: Putative aconitase, subunit; PFAM: Protein of unknown function DUF126. (111 aa)    
Predicted Functional Partners:
ADV65001.1
Putative aconitase subunit 1; COGs: COG1679 conserved hypothetical protein; InterPro IPR007506; KEGG: dka:DKAM_0143 putative aconitase subunit 1; PFAM: protein of unknown function DUF521; SPTR: Putative aconitase subunit 1; PFAM: Protein of unknown function (DUF521).
 
 
 0.986
tmk
COGs: COG0125 Thymidylate kinase; InterPro IPR018094: IPR018095: IPR000062; KEGG: dka:DKAM_0141 thymidylate kinase; PFAM: thymidylate kinase; PRIAM: dTMP kinase; SPTR: Probable thymidylate kinase; TIGRFAM: thymidylate kinase; PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase.
       0.880
ADV65002.1
Carboxylyase-related protein; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR017871: IPR002830; KEGG: dka:DKAM_0144 UbiD family decarboxylase; PFAM: Carboxylyase-related protein; SPTR: UbiD family decarboxylase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases.
 
     0.854
ADV65003.1
COGs: COG1341 GTPase or GTP-binding protein; KEGG: dka:DKAM_0145 putative GTPase or GTP-binding protein; SPTR: Putative GTPase or GTP-binding protein; PFAM: Molybdopterin guanine dinucleotide synthesis protein B.
 
     0.823
ADV65004.1
KEGG: dka:DKAM_0146 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.752
ADV65006.1
Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
       0.566
ADV65005.1
AAA ATPase; COGs: COG0468 RecA/RadA recombinase; InterPro IPR003593; KEGG: dka:DKAM_0147 AAA ATPase; SMART: AAA ATPase; SPTR: AAA ATPase.
       0.528
tiaS
tRNA(Ile2) 2-agmatinylcytidine synthetase; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
  
     0.476
ADV64997.1
Protein of unknown function UPF0147; COGs: COG1698 conserved hypothetical protein; InterPro IPR005354; KEGG: dka:DKAM_0139 hypothetical protein; PFAM: protein of unknown function UPF0147; SPTR: UPF0147 protein DKAM_0139; PFAM: Uncharacterised protein family (UPF0147); Belongs to the UPF0147 family.
  
     0.456
csl4
RNA-binding protein (consists of S1 domain and a Zn-ribbon domain); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.
  
     0.450
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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