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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65002.1Carboxylyase-related protein; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR017871: IPR002830; KEGG: dka:DKAM_0144 UbiD family decarboxylase; PFAM: Carboxylyase-related protein; SPTR: UbiD family decarboxylase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases. (426 aa)    
Predicted Functional Partners:
ubiX
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
 
  
 0.953
ADV65001.1
Putative aconitase subunit 1; COGs: COG1679 conserved hypothetical protein; InterPro IPR007506; KEGG: dka:DKAM_0143 putative aconitase subunit 1; PFAM: protein of unknown function DUF521; SPTR: Putative aconitase subunit 1; PFAM: Protein of unknown function (DUF521).
 
     0.921
ADV65003.1
COGs: COG1341 GTPase or GTP-binding protein; KEGG: dka:DKAM_0145 putative GTPase or GTP-binding protein; SPTR: Putative GTPase or GTP-binding protein; PFAM: Molybdopterin guanine dinucleotide synthesis protein B.
       0.881
ADV65004.1
KEGG: dka:DKAM_0146 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.873
ADV65000.1
Protein of unknown function DUF126; COGs: COG1786 conserved hypothetical protein; InterPro IPR002840; KEGG: dka:DKAM_0142 putative aconitase, subunit; PFAM: protein of unknown function DUF126; SPTR: Putative aconitase, subunit; PFAM: Protein of unknown function DUF126.
 
     0.854
tmk
COGs: COG0125 Thymidylate kinase; InterPro IPR018094: IPR018095: IPR000062; KEGG: dka:DKAM_0141 thymidylate kinase; PFAM: thymidylate kinase; PRIAM: dTMP kinase; SPTR: Probable thymidylate kinase; TIGRFAM: thymidylate kinase; PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase.
       0.772
ADV65005.1
AAA ATPase; COGs: COG0468 RecA/RadA recombinase; InterPro IPR003593; KEGG: dka:DKAM_0147 AAA ATPase; SMART: AAA ATPase; SPTR: AAA ATPase.
 
     0.695
ADV65006.1
Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
       0.677
ADV64488.1
Sulfide dehydrogenase (flavoprotein) subunit SudB; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterProIPR017927: IPR012165: IPR008333: IPR001433: IPR 019480; KEGG: kcr:Kcr_0345 ferredoxin-NADP(+) reductase subunit alpha; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: Oxidoreductase FAD/NAD(P)-binding domain protein; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of di [...]
  
    0.588
ADV64872.1
Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulfur cluster binding domain protein; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterProIPR017927: IPR012165: IPR006058: IPR001433: IPR 019480; KEGG: dka:DKAM_0475 probable dihydroorotate dehydrogenase electron transfer subunit; PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; oxidoreductase FAD/NAD(P)-binding domain protein; SPTR: Probable dihydroorotate dehydrogenase electron transfer subunit; PFAM: Iron-sulfur cluster binding dom [...]
  
    0.588
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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