close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65006.1Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. (170 aa)    
Predicted Functional Partners:
ADV64383.1
Geranylgeranylglycerol-phosphate geranylgeranyltransferase; COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR000537; KEGG: dka:DKAM_1012 UbiA prenyltransferase; PFAM: UbiA prenyltransferase; PRIAM: Geranylgeranylglycerol-phosphate geranylgeranyltransferase; SPTR: ORF 1; PFAM: UbiA prenyltransferase family.
 
  
 0.953
ADV64609.1
2,3-di-O-geranylgeranylglyceryl phosphate reductase; COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR011777: IPR003042: IPR003953; KEGG: dka:DKAM_0159 geranylgeranyl reductase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: Geranylgeranyl reductase; TIGRFAM: geranylgeranyl reductase; PFAM: Lycopene cyclase protein; TIGRFAM: geranylgeranyl reductase family.
  
  
 0.927
ADV65005.1
AAA ATPase; COGs: COG0468 RecA/RadA recombinase; InterPro IPR003593; KEGG: dka:DKAM_0147 AAA ATPase; SMART: AAA ATPase; SPTR: AAA ATPase.
 
     0.895
ADV65002.1
Carboxylyase-related protein; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR017871: IPR002830; KEGG: dka:DKAM_0144 UbiD family decarboxylase; PFAM: Carboxylyase-related protein; SPTR: UbiD family decarboxylase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases.
       0.677
ADV65004.1
KEGG: dka:DKAM_0146 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.675
ADV65003.1
COGs: COG1341 GTPase or GTP-binding protein; KEGG: dka:DKAM_0145 putative GTPase or GTP-binding protein; SPTR: Putative GTPase or GTP-binding protein; PFAM: Molybdopterin guanine dinucleotide synthesis protein B.
       0.660
ADV65001.1
Putative aconitase subunit 1; COGs: COG1679 conserved hypothetical protein; InterPro IPR007506; KEGG: dka:DKAM_0143 putative aconitase subunit 1; PFAM: protein of unknown function DUF521; SPTR: Putative aconitase subunit 1; PFAM: Protein of unknown function (DUF521).
       0.657
ADV64469.1
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
   
    0.648
ADV65546.1
PUA domain containing protein; COGs: COG1370 Prefoldin molecular chaperone implicated in de novo protein folding alpha subunit; InterPro IPR002478: IPR004521; KEGG: dka:DKAM_1256 prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit; PFAM: PUA domain containing protein; SMART: PUA domain containing protein; SPTR: Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit; PFAM: PUA domain; TIGRFAM: uncharacterized domain 2.
  
     0.605
ADV65000.1
Protein of unknown function DUF126; COGs: COG1786 conserved hypothetical protein; InterPro IPR002840; KEGG: dka:DKAM_0142 putative aconitase, subunit; PFAM: protein of unknown function DUF126; SPTR: Putative aconitase, subunit; PFAM: Protein of unknown function DUF126.
       0.566
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.