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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65033.1Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838: IPR004839: IPR001176; KEGG: dka:DKAM_0468 aspartate aminotransferase (AspC), conjectural; PFAM: aminotransferase class I and II; SPTR: Aspartate aminotransferase (AspC), conjectural; PFAM: Aminotransferase class I and II. (425 aa)    
Predicted Functional Partners:
ADV64952.1
COGs: COG0031 Cysteine synthase; InterPro IPR001216: IPR001926; KEGG: tag:Tagg_1314 pyridoxal-5'-phosphate-dependent protein subunit beta; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme.
 
 0.941
ADV65088.1
COGs: COG0031 Cysteine synthase; InterPro IPR001216: IPR001926; KEGG: dka:DKAM_0378 pyridoxal-5'-phosphate-dependent enzyme, beta subunit; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme.
 
 0.941
ADV64465.1
COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006095: IPR014362: IPR006097: IPR006096; KEGG: dka:DKAM_1451 Glu/Leu/Phe/Val dehydrogenase, C terminal; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; SPTR: Glu/Leu/Phe/Val dehydrogenase, C terminal; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.940
ADV64511.1
COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterPro IPR002129; KEGG: dka:DKAM_0021 pyridoxal-dependent decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; SPTR: Pyridoxal-dependent decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain; TIGRFAM: tyrosine decarboxylase MnfA.
  
 
 0.940
ADV64380.1
Sulfide dehydrogenase (flavoprotein) subunit SudA; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027: IPR000103; KEGG: dka:DKAM_1015 putative glutamate synthase subunit beta; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Putative glutamate synthase subunit beta; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.929
pyrB
COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR002082: IPR006130: IPR006132: IPR006131; KEGG: dka:DKAM_0742 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase.
    
 0.920
ADV64902.1
Asparaginase; COGs: COG1446 Asparaginase; InterPro IPR000246; KEGG: dka:DKAM_0544 asparaginase; PFAM: peptidase T2 asparaginase 2; SPTR: Asparaginase; PFAM: Asparaginase.
   
 0.909
ADV65032.1
Conserved carboxylase region; COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000891: IPR003379; KEGG: dka:DKAM_0467 pyruvate/oxaloacetate carboxyltransferase; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; SPTR: Pyruvate/oxaloacetate carboxyltransferase; PFAM: HMGL-like; Conserved carboxylase domain.
    
 0.907
ADV65046.1
COGs: COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; InterPro IPR005252: IPR003382: IPR007085; KEGG: dka:DKAM_0332 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein; SPTR: Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA / pantothenate metabolism flavoprotein; Flavoprotein; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothen [...]
 
  0.899
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
  
 
 0.872
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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