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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65055.1Phosphomethylpyrimidine kinase; COGs: COG1992 conserved hypothetical protein; InterPro IPR019293; KEGG: dka:DKAM_0343 transcriptional regulator, fis family; PFAM: Phosphomethylpyrimidine kinase; SPTR: Transcriptional regulator, Fis family; PFAM: Archaeal phosphomethylpyrimidine kinase. (291 aa)    
Predicted Functional Partners:
ADV65056.1
KEGG: dka:DKAM_0344 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.879
ADV65054.1
Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
       0.877
panB
Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
       0.770
ADV65057.1
ABC transporter related protein; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR017871: IPR003439: IPR003593; KEGG: dka:DKAM_0346 daunorubicin resistance ATP-binding protein-like protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Daunorubicin resistance ATP-binding protein-like protein; PFAM: ABC transporter.
 
     0.706
ADV65058.1
ABC-2 type transporter; COGs: COG1668 ABC-type Na+ efflux pump permease component; KEGG: dka:DKAM_0347 ABC-2 type transporter; SPTR: ABC-2 type transporter.
 
     0.700
ADV65062.1
Alpha-amylase; COGs: COG1449 Alpha-amylase/alpha-mannosidase; InterPro IPR018483: IPR015178: IPR004300: IPR015179; KEGG: dka:DKAM_0351 glycoside hydrolase, family 57; PFAM: Domain of unknown function DUF1925; glycoside hydrolase family 57; Domain of unknown function DUF1926; PRIAM: 4-alpha-glucanotransferase; SPTR: Glycoside hydrolase, family 57; PFAM: Domain of unknown function (DUF1925); Glycosyl hydrolase family 57; Domain of unknown function (DUF1926).
 
     0.555
ADV65060.1
Alpha amylase; COGs: COG3281 Uncharacterized protein probably involved in trehalose biosynthesis; KEGG: dka:DKAM_0349 alpha amylase; SPTR: Alpha amylase.
       0.496
ADV65061.1
Alpha-amylase; COGs: COG1449 Alpha-amylase/alpha-mannosidase; InterPro IPR004300; KEGG: dka:DKAM_0350 alpha-amylase; PFAM: glycoside hydrolase family 57; PRIAM: Alpha-amylase; SPTR: Alpha-amylase; PFAM: Glycosyl hydrolase family 57.
       0.488
ADV65059.1
Regulatory protein, MarR; InterPro IPR005471; KEGG: dka:DKAM_0348 regulatory protein, MarR; SPTR: Regulatory protein, MarR; PFAM: Sugar-specific transcriptional regulator TrmB.
       0.469
fau-1
Protein of unknown function DUF402; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.
  
     0.464
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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