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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65069.1Serine protease-like protein; COGs: COG1750 serine protease; InterPro IPR001984; KEGG: dka:DKAM_0359 serine proteases-like protein; SPTR: Serine proteases-like protein; PFAM: Lon protease (S16) C-terminal proteolytic domain. (655 aa)    
Predicted Functional Partners:
htpX
Heat shock protein; COGs: COG0501 Zn-dependent protease with chaperone function; InterPro IPR001915; KEGG: dka:DKAM_0358 probable protease HtpX - like protein; PFAM: peptidase M48 Ste24p; SPTR: Probable protease htpX-like protein; PFAM: Peptidase family M48; Belongs to the peptidase M48B family.
 
     0.546
ADV65303.1
KEGG: fpl:Ferp_1869 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2276).
  
     0.402
ADV65070.1
Phosphoesterase; COGs: COG1407 ICC-like phosphoesterase; InterPro IPR004376: IPR004843; KEGG: dka:DKAM_0360 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: Metallophosphoesterase; TIGRFAM: phosphoesterase; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: putative phosphoesterase, SbcD/Mre11-related.
       0.400
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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