close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65116.1KEGG: dka:DKAM_0413 hypothetical protein; SPTR: Putative uncharacterized protein. (87 aa)    
Predicted Functional Partners:
ADV65115.1
InterPro IPR007182; KEGG: dka:DKAM_0412 Na+/H+ antiporter, MnhB subunit; PFAM: Na+/H+ antiporter MnhB subunit-related protein; SPTR: Na+/H+ antiporter, MnhB subunit; PFAM: Domain related to MnhB subunit of Na+/H+ antiporter.
   
 
 0.965
ADV65113.1
Membrane bound protein complex subunit mbxA; COGs: COG1863 Multisubunit Na+/H+ antiporter MnhE subunit; InterPro IPR002758; KEGG: dka:DKAM_0410 putative integral membrane protein, DUF68 family; PFAM: cation antiporter; SPTR: Putative integral membrane protein, DUF68 family; PFAM: Na+/H+ ion antiporter subunit.
  
 
 0.934
ADV65117.1
Monovalent cation/proton antiporter, MnhG/PhaG subunit; COGs: COG1320 Multisubunit Na+/H+ antiporter MnhG subunit; InterPro IPR005133; KEGG: dka:DKAM_0414 Na+/H+ antiporter, MnhG subunit; PFAM: Na+/H+ antiporter subunit; SPTR: Na+/H+ antiporter, MnhG subunit; TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit; TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit.
  
 
 0.933
ADV65114.1
NADH-ubiquinone oxidoreductase chain 4L; COGs: COG1006 Multisubunit Na+/H+ antiporter MnhC subunit; InterPro IPR001133; KEGG: dka:DKAM_0411 NADH-ubiquinone oxidoreductase, chain 4L; PFAM: NADH-ubiquinone oxidoreductase chain 4L; SPTR: NADH-ubiquinone oxidoreductase, chain 4L; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L.
  
 
 0.925
ADV65120.1
NADH-ubiquinone oxidoreductase chain 49kDa; COGs: COG3261 Ni Fe-hydrogenase III large subunit; InterPro IPR001135; KEGG: dka:DKAM_0417 NADH-ubiquinone oxidoreductase, chain 49 kDa; PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; SPTR: NADH-ubiquinone oxidoreductase, chain 49 kDa; PFAM: Respiratory-chain NADH dehydrogenase, 49 Kd subunit; Nickel-dependent hydrogenase.
   
 
 0.920
ADV65112.1
Membrane bound hydrogenase subunit mbhH; COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR001750; KEGG: dka:DKAM_0409 putative monovalent cation/H+ antiporter subunit D; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: Hydrogenase 4, component F or formate hydrogen lyase; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains.
  
 
 0.919
ADV65118.1
Multiple resistance and pH regulation protein F; InterPro IPR007208; KEGG: dka:DKAM_0415 Na+/H+ antiporter MnhF subunit; PFAM: multiple resistance and pH regulation protein F; SPTR: Na+/H+ antiporter MnhF subunit; PFAM: Multiple resistance and pH regulation protein F (MrpF / PhaF).
   
   0.916
ADV65119.1
COGs: COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); InterPro IPR017900: IPR017896; KEGG: dka:DKAM_0416 NADH-ubiquinone oxidoreductase, subunit I; SPTR: NADH-ubiquinone oxidoreductase, subunit I; PFAM: 4Fe-4S binding domain.
   
   0.915
ADV65121.1
NADH dehydrogenase (ubiquinone) 30 kDa subunit; COGs: COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit; InterPro IPR001268; KEGG: dka:DKAM_0418 NADH dehydrogenase (ubiquinone), 30 kDa subunit; PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; SPTR: NADH dehydrogenase (Ubiquinone), 30 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit.
   
   0.914
ADV65122.1
COGs: COG3260 Ni Fe-hydrogenase III small subunit; InterPro IPR006138: IPR006137; KEGG: dka:DKAM_0419 NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase, B subunit; TIGRFAM: NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, B subunit; Belongs to the complex I 20 kDa subunit family.
   
   0.913
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.