close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65153.1COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterPro IPR004531: IPR005146: IPR005147: IPR002319; KEGG: dka:DKAM_0189 phenylalanyl-tRNA synthetase subunit beta; PFAM: tRNA synthetase B5; B3/4 domain protein; phenylalanyl-tRNA synthetase class IIc; PRIAM: Phenylalanine--tRNA ligase; SPTR: Phenylalanyl-tRNA synthetase subunit beta; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit. (554 aa)    
Predicted Functional Partners:
ADV65267.1
COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; InterPro IPR004529: IPR002319: IPR006195; KEGG: dka:DKAM_0237 phenylalanyl-tRNA synthetase subunit alpha; PFAM: phenylalanyl-tRNA synthetase class IIc; SPTR: PheS; phenylalanyl-tRNA synthetase subunit alpha; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: tRNA synthetases class II core domain (F); TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit.
 
 0.999
ADV64824.1
COGs: COG0495 Leucyl-tRNA synthetase; InterProIPR001412: IPR004493: IPR015413: IPR020754: IPR 013155; KEGG: dka:DKAM_0624 leucyl-tRNA synthetase; PFAM: tRNA synthetase valyl/leucyl anticodon-binding; tRNA synthetase class I (M); Lysyl-tRNA synthetase, class Ic; SPTR: Leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, archaeal and cytosolic family; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.940
rps3
SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
 
 
 0.905
ADV64876.1
COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR017926: IPR006220: IPR011702: IPR004739: IPR 001674: IPR000991; KEGG: dka:DKAM_0479 GMP synthase; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; SPTR: GMP synthase; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase C terminal domain; Glutamine amidotransferase class-I; NAD synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit.
  
  
 0.904
ileS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
 
 
 0.887
ADV65152.1
KEGG: dka:DKAM_0188 aminopeptidases-like protein; SPTR: Aminopeptidases-like protein; PFAM: Peptidase family M28.
     
 0.874
rps19p
SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
  
 
 0.871
rps17
SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
 
 
 0.854
rps9
COGs: COG0103 Ribosomal protein S9; InterPro IPR000754: IPR019958: IPR020574; KEGG: dka:DKAM_1360 30S ribosomal protein S9P; PFAM: ribosomal protein S9; SPTR: 30S ribosomal protein S9P; TIGRFAM: ribosomal protein S9P; PFAM: Ribosomal protein S9/S16; TIGRFAM: archaeal ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family.
 
 
 0.839
thrS
COGs: COG0441 Threonyl-tRNA synthetase; InterProIPR018158: IPR002320: IPR015011: IPR002314: IPR 004154: IPR006195; KEGG: dka:DKAM_1216 threonyl-tRNA synthetase; PFAM: Threonyl-tRNA synthetase editing domain-containing protein; tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; SPTR: Threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); Archaea-specific editing domain of threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA [...]
 
 
 0.832
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.