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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65154.1Sodium/hydrogen exchanger; COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR006153; KEGG: dka:DKAM_0190 putative Na+/H+ antiporter; PFAM: sodium/hydrogen exchanger; SPTR: Putative Na+/H+ antiporter; PFAM: Sodium/hydrogen exchanger family. (385 aa)    
Predicted Functional Partners:
ADV64476.1
ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR018303: IPR001757: IPR000695: IPR004014: IPR 008250: IPR005834; KEGG: dka:DKAM_1201 H+-transporting ATPase related protein; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: H+-transporting ATPase related protein; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; Cation transporter/ATPase, N-terminus; TIGRF [...]
 
 
 0.648
ADV65155.1
KEGG: dka:DKAM_0191 protein of unknown function (DUF1210); SPTR: Putative uncharacterized protein.
       0.597
ADV64876.1
COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR017926: IPR006220: IPR011702: IPR004739: IPR 001674: IPR000991; KEGG: dka:DKAM_0479 GMP synthase; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; SPTR: GMP synthase; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase C terminal domain; Glutamine amidotransferase class-I; NAD synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit.
       0.515
hflX
GTP-binding proten HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
 
   
 0.502
ADV65407.1
Cation transporter; COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: dka:DKAM_1090 cation transporter; PFAM: cation transporter; SPTR: Cation transporter; PFAM: Cation transport protein.
  
 
 0.492
ADV65397.1
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148: IPR006037; KEGG: dka:DKAM_1079 TrkA-N domain protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: TrkA-N domain protein; PFAM: TrkA-N domain.
     
 0.480
ADV65289.1
MATE efflux family protein; COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: dka:DKAM_0200 MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: MATE efflux family protein; manually curated; PFAM: MatE; TIGRFAM: putative efflux protein, MATE family.
 
  
 0.467
ADV65363.1
COGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); InterPro IPR004666: IPR013651: IPR011761; KEGG: dka:DKAM_1049 alpha-L-glutamate ligase, RimK family; PFAM: RimK domain protein ATP-grasp; SPTR: Alpha-L-glutamate ligase, RimK family; TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: RimK-like ATP-grasp domain; TIGRFAM: alpha-L-glutamate ligases, RimK family.
     
 0.416
ADV64531.1
Small GTP-binding protein; COGs: COG0370 Fe2+ transport system protein B; InterProIPR005225: IPR006073: IPR002917: IPR011619: IPR 011642; KEGG: dka:DKAM_0070 ferrous iron transport protein B; PFAM: GTP-binding protein HSR1-related; Ferrous iron transport protein B domain-containing protein; nucleoside recognition domain protein; SPTR: Ferrous iron transport protein B; TIGRFAM: small GTP-binding protein; PFAM: Ferrous iron transport protein B; Ferrous iron transport protein B C terminus; Nucleoside recognition; TIGRFAM: ferrous iron transporter FeoB; small GTP-binding protein domain.
 
   
 0.413
ADV64415.1
Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR018303: IPR006121: IPR006416: IPR001757: IPR 008250: IPR005834; KEGG: tag:Tagg_1238 heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Heavy metal translocating P-type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type [...]
  
  
 0.405
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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