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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65180.1KEGG: dka:DKAM_0825 amidohydrolase-like protein; SPTR: Amidohydrolase-like protein. (298 aa)    
Predicted Functional Partners:
rgy
Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
       0.882
ADV65179.1
KEGG: dka:DKAM_0824 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.812
ADV64876.1
COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR017926: IPR006220: IPR011702: IPR004739: IPR 001674: IPR000991; KEGG: dka:DKAM_0479 GMP synthase; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; SPTR: GMP synthase; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase C terminal domain; Glutamine amidotransferase class-I; NAD synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit.
   
 
 0.755
ADV65182.1
COGs: COG0591 Na+/proline symporter; InterPro IPR001734; KEGG: dka:DKAM_0827 sodium/solute symporter; PFAM: Na+/solute symporter; SPTR: Sodium/solute symporter; PFAM: Sodium:solute symporter family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
     
 0.681
ADV65183.1
KEGG: dka:DKAM_0828 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.607
ADV64465.1
COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006095: IPR014362: IPR006097: IPR006096; KEGG: dka:DKAM_1451 Glu/Leu/Phe/Val dehydrogenase, C terminal; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; SPTR: Glu/Leu/Phe/Val dehydrogenase, C terminal; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
  
 0.507
ADV64546.1
Agmatinase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR020855: IPR006035: IPR005925; KEGG: dka:DKAM_0053 agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; SPTR: Agmatinase; TIGRFAM: agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; Belongs to the arginase family.
  
 0.503
ADV64536.1
Phosphate ABC transporter ATP-binding protein, PhoT family; COGs: COG1117 ABC-type phosphate transport system ATPase component; InterPro IPR017871: IPR003439: IPR003593; KEGG: dka:DKAM_0064 phosphate import ATP-binding protein PstB; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Phosphate import ATP-binding protein pstB; PFAM: ABC transporter.
   
    0.465
ADV65184.1
COGs: COG3888 transcriptional regulator protein; KEGG: dka:DKAM_0829 transcriptional regulator MarR family; SPTR: Transcriptional regulator MarR family.
       0.453
ADV65185.1
COGs: COG0035 Uracil phosphoribosyltransferase; KEGG: dka:DKAM_0830 uracil phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: uracil phosphoribosyltransferase.
       0.428
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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