close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65184.1COGs: COG3888 transcriptional regulator protein; KEGG: dka:DKAM_0829 transcriptional regulator MarR family; SPTR: Transcriptional regulator MarR family. (340 aa)    
Predicted Functional Partners:
ADV65185.1
COGs: COG0035 Uracil phosphoribosyltransferase; KEGG: dka:DKAM_0830 uracil phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: uracil phosphoribosyltransferase.
       0.675
ADV65182.1
COGs: COG0591 Na+/proline symporter; InterPro IPR001734; KEGG: dka:DKAM_0827 sodium/solute symporter; PFAM: Na+/solute symporter; SPTR: Sodium/solute symporter; PFAM: Sodium:solute symporter family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
       0.605
ADV65183.1
KEGG: dka:DKAM_0828 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.592
ADV65180.1
KEGG: dka:DKAM_0825 amidohydrolase-like protein; SPTR: Amidohydrolase-like protein.
       0.453
rgy
Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
       0.453
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.