close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65199.1Phosphoesterase; KEGG: dka:DKAM_0845 phosphoesterase; SPTR: Phosphoesterase. (194 aa)    
Predicted Functional Partners:
ADV65198.1
COGs: COG1665 conserved hypothetical protein; KEGG: dka:DKAM_0844 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.880
ADV65200.1
Branched-chain acyl-CoA synthetase (ADP-forming) alpha subunit; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR014089: IPR003781; KEGG: dka:DKAM_0846 acetyl-CoA synthetase; PFAM: CoA-binding domain protein; SPTR: Acetyl-CoA synthetase; TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain protein; PFAM: CoA binding domain; TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain; acetyl-CoA synthetase (ADP-forming) alpha subunit.
       0.702
ADV65197.1
KEGG: dka:DKAM_0843 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.648
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.