close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65208.1InterPro IPR003115; KEGG: dka:DKAM_0858 ParB domain protein nuclease; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: ParB domain protein nuclease; PFAM: ParB-like nuclease domain. (255 aa)    
Predicted Functional Partners:
ADV64952.1
COGs: COG0031 Cysteine synthase; InterPro IPR001216: IPR001926; KEGG: tag:Tagg_1314 pyridoxal-5'-phosphate-dependent protein subunit beta; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme.
    
 0.929
ADV65088.1
COGs: COG0031 Cysteine synthase; InterPro IPR001216: IPR001926; KEGG: dka:DKAM_0378 pyridoxal-5'-phosphate-dependent enzyme, beta subunit; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme.
    
 0.929
ADV64756.1
Hypothetical protein; COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: sii:LD85_3138 hypothetical protein; SPTR: Cobyrinic acid ac-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
 
 
 0.928
ADV65163.1
COGs: COG0560 Phosphoserine phosphatase; InterPro IPR006383: IPR005834; KEGG: dka:DKAM_0808 phosphoserine phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Phosphoserine phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; HAD-superfamily, subfamily-IB PSPase-like hydrolase, archaeal.
  
 
  0.903
ADV65209.1
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006140: IPR006139; KEGG: dka:DKAM_0857 phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: Phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.
 
   
 0.887
ADV65210.1
COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR020578: IPR000192; KEGG: dka:DKAM_0918 aspartate/serine transaminase; PFAM: aminotransferase class V; SPTR: Aspartate/serine transaminase; PFAM: Aminotransferase class-V.
 
   
 0.734
ADV64876.1
COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR017926: IPR006220: IPR011702: IPR004739: IPR 001674: IPR000991; KEGG: dka:DKAM_0479 GMP synthase; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; SPTR: GMP synthase; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase C terminal domain; Glutamine amidotransferase class-I; NAD synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit.
     
 0.587
ADV64782.1
Protein of unknown function DUF996; COGs: COG2245 membrane protein; InterPro IPR010397; KEGG: dka:DKAM_0701 protein of unknown function (DUF996); PFAM: protein of unknown function DUF996; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF996).
  
     0.527
ADV64894.1
dephospho-CoA kinase, CoaE; COGs: COG0237 Dephospho-CoA kinase; KEGG: dka:DKAM_0323 dephospho-CoA kinase, CoaE; SPTR: Dephospho-CoA kinase, CoaE; Belongs to the UPF0200 family.
 
   
 0.469
ADV65238.1
DNA methylase N-4/N-6 domain protein; COGs: COG1041 DNA modification methylase; InterPro IPR001091: IPR002941; KEGG: tag:Tagg_1290 putative RNA methylase; PFAM: DNA methylase N-4/N-6 domain protein; SPTR: Putative RNA methylase; PFAM: DNA methylase.
  
  
 0.468
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
Server load: medium (48%) [HD]