close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65234.1MoaD family protein; InterPro IPR010038: IPR003749; KEGG: dka:DKAM_0893 molybdopterin converting factor, small subunit; PFAM: thiamineS protein; SPTR: Molybdopterin converting factor, small subunit; TIGRFAM: MoaD family protein; PFAM: ThiS family; TIGRFAM: MoaD family protein, archaeal. (96 aa)    
Predicted Functional Partners:
ADV65277.1
Molybdopterin biosynthesis MoaE protein; COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: dka:DKAM_0211 MoaD family protein; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: MoaD family protein; PFAM: MoaE protein.
  
 0.991
ADV64331.1
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594: IPR007901; KEGG: dka:DKAM_1387 MoeB/ThiF molybdopterin or thiamine synthase protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; SPTR: MoeB/thiF molybdopterin or thiamine synthase protein; PFAM: MoeZ/MoeB domain; ThiF family.
  
 0.974
ADV64332.1
thiamineS protein; InterPro IPR003749; KEGG: dka:DKAM_1388 molybdopterin converting factor, small subunit; PFAM: thiamineS protein; SPTR: Molybdopterin converting factor, small subunit; PFAM: ThiS family.
     
  0.900
ADV64837.1
thiamineS protein; InterPro IPR003749; KEGG: dka:DKAM_0734 thiamineS protein; PFAM: thiamineS protein; SPTR: ThiamineS protein; PFAM: ThiS family; TIGRFAM: MoaD family protein, archaeal.
     
  0.900
ADV65276.1
thiamineS protein; InterPro IPR003749; KEGG: dka:DKAM_0212 MoaD family protein; PFAM: thiamineS protein; SPTR: MoaD family protein; PFAM: ThiS family.
     
  0.900
ADV65233.1
COGs: COG2388 acetyltransferase; InterPro IPR000182; KEGG: dka:DKAM_0894 predicted acetyltransferase; SPTR: Predicted acetyltransferase; PFAM: Acetyltransferase (GNAT) family.
       0.830
moaC
GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
  
 0.734
ADV64769.1
COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR020817: IPR005110: IPR001453: IPR005111; KEGG: dka:DKAM_0715 putative molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing protein; PFAM: MoeA domain protein domain I and II; molybdopterin binding domain; MoeA domain protein domain IV; SPTR: Molybdenum cofactor synthesis domain protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesi [...]
  
  
 0.698
ADV65274.1
GTP cyclohydrolase subunit MoaA; COGs: COG2896 Molybdenum cofactor biosynthesis protein; InterPro IPR007197: IPR010505: IPR006638; KEGG: dka:DKAM_0214 probable molybdenum cofactor biosynthesis protein A; PFAM: Radical SAM domain protein; molybdenum cofactor synthesis domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Probable molybdenum cofactor biosynthesis protein A; PFAM: Molybdenum Cofactor Synthesis C; Radical SAM superfamily; TIGRFAM: probable molybdenum cofactor biosynthesis protein A, archaeal.
  
  
 0.682
rpl44e
LSU ribosomal protein L44E; Binds to the 23S rRNA.
       0.594
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.