close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65269.1Protein of unknown function DUF89; COGs: COG1578 conserved hypothetical protein; InterPro IPR014444: IPR002791; KEGG: dka:DKAM_0219 protein of unknown function DUF89; PFAM: protein of unknown function DUF89; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF89. (299 aa)    
Predicted Functional Partners:
ADV65270.1
Molybdopterin binding domain protein; COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR001453; KEGG: dka:DKAM_0218 molybdopterin binding domain protein; PFAM: molybdopterin binding domain; SPTR: Molybdopterin binding domain protein; PFAM: Probable molybdopterin binding domain.
       0.542
ADV65271.1
COGs: COG0725 ABC-type molybdate transport system periplasmic component; InterPro IPR005950; KEGG: dka:DKAM_0217 molybdenum ABC transporter, periplasmic molybdate-binding protein; SPTR: Molybdenum ABC transporter, periplasmic molybdate-binding protein; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein.
       0.542
ADV65272.1
Binding-protein-dependent transport systems inner membrane component; COGs: COG4149 ABC-type molybdate transport system permease component; InterPro IPR000515; KEGG: dka:DKAM_0216 molybdate ABC transporter, permease protein ModB; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Molybdate ABC transporter, permease protein ModB; PFAM: Binding-protein-dependent transport system inner membrane component.
       0.542
ADV65273.1
ABC transporter related protein; COGs: COG3839 ABC-type sugar transport systems ATPase components; InterPro IPR003439: IPR003593; KEGG: dka:DKAM_0215 glycine betaine/carnitine/choline transport ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Glycine betaine/carnitine/choline transport ATP-binding protein; PFAM: ABC transporter.
       0.542
ADV65274.1
GTP cyclohydrolase subunit MoaA; COGs: COG2896 Molybdenum cofactor biosynthesis protein; InterPro IPR007197: IPR010505: IPR006638; KEGG: dka:DKAM_0214 probable molybdenum cofactor biosynthesis protein A; PFAM: Radical SAM domain protein; molybdenum cofactor synthesis domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Probable molybdenum cofactor biosynthesis protein A; PFAM: Molybdenum Cofactor Synthesis C; Radical SAM superfamily; TIGRFAM: probable molybdenum cofactor biosynthesis protein A, archaeal.
       0.542
moaC
GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
       0.542
ADV65277.1
Molybdopterin biosynthesis MoaE protein; COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: dka:DKAM_0211 MoaD family protein; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: MoaD family protein; PFAM: MoaE protein.
       0.542
ADV65276.1
thiamineS protein; InterPro IPR003749; KEGG: dka:DKAM_0212 MoaD family protein; PFAM: thiamineS protein; SPTR: MoaD family protein; PFAM: ThiS family.
       0.529
ADV64522.1
Hypothetical protein; COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: pho:PH0874 hypothetical protein; SPTR: Putative uncharacterized protein PH0874; PFAM: Metallo-beta-lactamase superfamily.
 
     0.468
ADV64529.1
COGs: COG1433 conserved hypothetical protein; InterPro IPR003731; KEGG: dka:DKAM_0553 dinitrogenase iron-molybdenum cofactor biosynthesis protein; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; SPTR: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; PFAM: Dinitrogenase iron-molybdenum cofactor.
 
     0.421
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
Server load: low (22%) [HD]