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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65274.1GTP cyclohydrolase subunit MoaA; COGs: COG2896 Molybdenum cofactor biosynthesis protein; InterPro IPR007197: IPR010505: IPR006638; KEGG: dka:DKAM_0214 probable molybdenum cofactor biosynthesis protein A; PFAM: Radical SAM domain protein; molybdenum cofactor synthesis domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Probable molybdenum cofactor biosynthesis protein A; PFAM: Molybdenum Cofactor Synthesis C; Radical SAM superfamily; TIGRFAM: probable molybdenum cofactor biosynthesis protein A, archaeal. (310 aa)    
Predicted Functional Partners:
moaC
GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
 0.999
ADV65277.1
Molybdopterin biosynthesis MoaE protein; COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: dka:DKAM_0211 MoaD family protein; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: MoaD family protein; PFAM: MoaE protein.
 
 
 0.971
ADV64769.1
COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR020817: IPR005110: IPR001453: IPR005111; KEGG: dka:DKAM_0715 putative molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing protein; PFAM: MoeA domain protein domain I and II; molybdopterin binding domain; MoeA domain protein domain IV; SPTR: Molybdenum cofactor synthesis domain protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesi [...]
 
 0.932
ADV65276.1
thiamineS protein; InterPro IPR003749; KEGG: dka:DKAM_0212 MoaD family protein; PFAM: thiamineS protein; SPTR: MoaD family protein; PFAM: ThiS family.
  
  
 0.925
ADV65130.1
Protein of unknown function DUF198; COGs: COG1469 conserved hypothetical protein; InterPro IPR003801; KEGG: dka:DKAM_0427 hypothetical protein; PFAM: protein of unknown function DUF198; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized ACR, COG1469.
    
  0.900
ADV65270.1
Molybdopterin binding domain protein; COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR001453; KEGG: dka:DKAM_0218 molybdopterin binding domain protein; PFAM: molybdopterin binding domain; SPTR: Molybdopterin binding domain protein; PFAM: Probable molybdopterin binding domain.
 
 
 0.894
ADV65271.1
COGs: COG0725 ABC-type molybdate transport system periplasmic component; InterPro IPR005950; KEGG: dka:DKAM_0217 molybdenum ABC transporter, periplasmic molybdate-binding protein; SPTR: Molybdenum ABC transporter, periplasmic molybdate-binding protein; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein.
  
  
 0.882
ADV64921.1
Molybdenum cofactor synthesis domain protein; COGs: COG0303 Molybdopterin biosynthesis enzyme; InterProIPR020817: IPR000463: IPR008284: IPR005110: IPR 001453: IPR005111; KEGG: dka:DKAM_0502 molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; molybdopterin binding domain; MoeA domain protein domain IV; SPTR: Molybdenum cofactor synthesis domain protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum co [...]
 
 0.877
ADV65272.1
Binding-protein-dependent transport systems inner membrane component; COGs: COG4149 ABC-type molybdate transport system permease component; InterPro IPR000515; KEGG: dka:DKAM_0216 molybdate ABC transporter, permease protein ModB; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Molybdate ABC transporter, permease protein ModB; PFAM: Binding-protein-dependent transport system inner membrane component.
 
  
 0.872
ADV65426.1
COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR012833; KEGG: tag:Tagg_0925 anaerobic ribonucleoside-triphosphate reductase; SPTR: Anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase.
    
 0.837
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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