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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65280.1InterPro IPR017900: IPR017896; KEGG: dka:DKAM_0208 4Fe-4S ferredoxin, iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain. (160 aa)    
Predicted Functional Partners:
ADV65281.1
Monooxygenase FAD-binding protein; COGs: COG0492 Thioredoxin reductase; InterProIPR006058: IPR013027: IPR000103: IPR002938: IPR 001327; KEGG: dka:DKAM_0207 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: monooxygenase FAD-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
  
 0.996
ADV65278.1
FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: dka:DKAM_0210 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase.
 
  
 0.963
ADV65279.1
InterPro IPR007419; KEGG: dka:DKAM_0209 BFD domain protein (2Fe-2S)-binding domain protein; PFAM: BFD domain protein [2Fe-2S]-binding domain protein; SPTR: BFD domain protein (2Fe-2S)-binding domain protein; PFAM: BFD-like [2Fe-2S] binding domain.
 
  
 0.928
ADV64374.1
NADH-ubiquinone oxidoreductase chain 49kDa; COGs: COG3261 Ni Fe-hydrogenase III large subunit; InterPro IPR001268: IPR014029: IPR001501: IPR001135; KEGG: dka:DKAM_1021 NADH dehydrogenase (ubiquinone), 30 kDa subunit; PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; NADH dehydrogenase (ubiquinone) 30 kDa subunit; nickel-dependent hydrogenase large subunit; SPTR: NADH dehydrogenase (Ubiquinone), 30 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit; Nickel-dependent hydrogenase.
  
 
 0.892
ADV64433.1
Tungsten-dependent formaldehyde:ferredoxin oxidoreductase; COGs: COG2414 Aldehyde:ferredoxin oxidoreductase; InterPro IPR013983: IPR001203; KEGG: dka:DKAM_0975 aldehyde ferredoxin oxidoreductase; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; PRIAM: Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; SPTR: Aldehyde ferredoxin oxidoreductase; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal domain; Aldehyde ferredoxin oxidoreductase, domains 2 & 3.
   
 
 0.773
ADV64924.1
COGs: COG2414 Aldehyde:ferredoxin oxidoreductase; InterPro IPR013983: IPR001203; KEGG: dka:DKAM_0499 aldehyde ferredoxin oxidoreductase-like protein; PFAM: Aldehyde ferredoxin oxidoreductase; aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; SPTR: Aldehyde ferredoxin oxidoreductase-like protein; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal domain; Aldehyde ferredoxin oxidoreductase, domains 2 & 3.
   
 
 0.773
ADV65120.1
NADH-ubiquinone oxidoreductase chain 49kDa; COGs: COG3261 Ni Fe-hydrogenase III large subunit; InterPro IPR001135; KEGG: dka:DKAM_0417 NADH-ubiquinone oxidoreductase, chain 49 kDa; PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; SPTR: NADH-ubiquinone oxidoreductase, chain 49 kDa; PFAM: Respiratory-chain NADH dehydrogenase, 49 Kd subunit; Nickel-dependent hydrogenase.
  
 
 0.746
ADV64773.1
COGs: COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); InterPro IPR000688; KEGG: dka:DKAM_0719 hydrogenase nickel incorporation protein; PFAM: hydrogenase expression/synthesis HypA; SPTR: Probable hydrogenase nickel incorporation protein; PFAM: Hydrogenase expression/synthesis hypA family.
  
  
 0.744
ADV64372.1
NADH ubiquinone oxidoreductase 20 kDa subunit; COGs: COG3260 Ni Fe-hydrogenase III small subunit; InterPro IPR006137; KEGG: dka:DKAM_1023 NADH ubiquinone oxidoreductase, 20 kDa subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; SPTR: NADH ubiquinone oxidoreductase, 20 kDa subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit.
  
 
 0.743
ADV65122.1
COGs: COG3260 Ni Fe-hydrogenase III small subunit; InterPro IPR006138: IPR006137; KEGG: dka:DKAM_0419 NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase, B subunit; TIGRFAM: NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, B subunit; Belongs to the complex I 20 kDa subunit family.
  
 
 0.743
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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