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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prf1Peptide chain release factor subunit 1 (aeRF-1); Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (361 aa)    
Predicted Functional Partners:
tuf
Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
  
 0.999
ADV65536.1
ABC transporter related protein; COGs: COG1245 ATPase RNase L inhibitor (RLI) homolog; InterProIPR003439: IPR017896: IPR003593: IPR007209: IPR 013283: IPR017900: IPR017871; KEGG: dka:DKAM_1248 putative ATPase RIL; PFAM: ABC transporter related; metal-binding domain in RNase L inhibitor, RLI; SMART: AAA ATPase; SPTR: Putative ATPase RIL; PFAM: ABC transporter; Possible metal-binding domain in RNase L inhibitor, RLI; 4Fe-4S binding domain.
  
 
 0.958
rpl15e
COGs: COG1632 Ribosomal protein L15E; InterPro IPR020926: IPR000439: IPR020925; KEGG: dka:DKAM_1331 50S ribosomal protein L15e; PFAM: Ribosomal protein L15e; SPTR: 50S ribosomal protein L15e; PFAM: Ribosomal L15; Belongs to the eukaryotic ribosomal protein eL15 family.
 
 0.909
rps3ae
COGs: COG1890 Ribosomal protein S3AE; InterPro IPR001593: IPR018281; KEGG: dka:DKAM_1335 30S ribosomal protein S3Ae; PFAM: ribosomal protein S3Ae; SPTR: 30S ribosomal protein S3Ae; PFAM: Ribosomal S3Ae family; Belongs to the eukaryotic ribosomal protein eS1 family.
  
  0.869
rpl10
LSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 0.868
rpl30
LSU ribosomal protein L30P; InterPro IPR005997: IPR000517; KEGG: dka:DKAM_1154 50S ribosomal protein L30P; PFAM: ribosomal protein L30; SPTR: 50S ribosomal protein L30P; TIGRFAM: ribosomal protein L30P; PFAM: Ribosomal protein L30p/L7e; TIGRFAM: 50S ribosomal protein L30P, archaeal.
  
 0.841
rps4e
COGs: COG1471 Ribosomal protein S4E; InterProIPR000289: IPR000876: IPR013843: IPR002942: IPR 013845; KEGG: dka:DKAM_1163 30S ribosomal protein S4e; PFAM: Ribosomal protein S4E, central domain protein; Ribosomal protein S4E domain protein; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: 30S ribosomal protein S4e; PFAM: S4 domain; Ribosomal family S4e; RS4NT (NUC023) domain; Belongs to the eukaryotic ribosomal protein eS4 family.
  
  0.840
rps6e
COGs: COG2125 Ribosomal protein S6E (S10); InterPro IPR001377: IPR018282; KEGG: dka:DKAM_1348 30S ribosomal protein S6e; PFAM: Ribosomal protein S6e; SPTR: 30S ribosomal protein S6e; PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 0.833
rpl24
LSU ribosomal protein L24P; Located at the polypeptide exit tunnel on the outside of the subunit.
  
  0.832
ADV64368.1
COGs: COG1093 Translation initiation factor 2 alpha subunit (eIF-2alpha); InterPro IPR003029: IPR011488; KEGG: dka:DKAM_1424 translation initiation factor IF-2 subunit alpha; PFAM: translation initiation factor 2, alpha subunit; RNA binding S1 domain protein; SPTR: Translation initiation factor IF-2 subunit alpha; PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain.
  
 
 0.817
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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