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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65351.1COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR008284: IPR001453; KEGG: dka:DKAM_0202 molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; SPTR: Molybdenum cofactor synthesis domain protein; manually curated; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. (164 aa)    
Predicted Functional Partners:
ADV65277.1
Molybdopterin biosynthesis MoaE protein; COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: dka:DKAM_0211 MoaD family protein; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: MoaD family protein; PFAM: MoaE protein.
  
 
 0.976
ADV64769.1
COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR020817: IPR005110: IPR001453: IPR005111; KEGG: dka:DKAM_0715 putative molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing protein; PFAM: MoeA domain protein domain I and II; molybdopterin binding domain; MoeA domain protein domain IV; SPTR: Molybdenum cofactor synthesis domain protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesi [...]
 
 0.974
ADV64921.1
Molybdenum cofactor synthesis domain protein; COGs: COG0303 Molybdopterin biosynthesis enzyme; InterProIPR020817: IPR000463: IPR008284: IPR005110: IPR 001453: IPR005111; KEGG: dka:DKAM_0502 molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; molybdopterin binding domain; MoeA domain protein domain IV; SPTR: Molybdenum cofactor synthesis domain protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum co [...]
 
 0.955
ADV65352.1
Haloacid dehalogenase domain protein hydrolase; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR019758: IPR005833: IPR005834; KEGG: dka:DKAM_0201 predicted hydrolase (HAD superfamily); PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Predicted hydrolase (HAD superfamily); PFAM: haloacid dehalogenase-like hydrolase.
 
   
 0.891
moaC
GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
  
 0.835
ADV65274.1
GTP cyclohydrolase subunit MoaA; COGs: COG2896 Molybdenum cofactor biosynthesis protein; InterPro IPR007197: IPR010505: IPR006638; KEGG: dka:DKAM_0214 probable molybdenum cofactor biosynthesis protein A; PFAM: Radical SAM domain protein; molybdenum cofactor synthesis domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Probable molybdenum cofactor biosynthesis protein A; PFAM: Molybdenum Cofactor Synthesis C; Radical SAM superfamily; TIGRFAM: probable molybdenum cofactor biosynthesis protein A, archaeal.
 
  
 0.734
ADV65350.1
methylated-DNA/protein- cysteinemethyltransferase; COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR001497: IPR014048; KEGG: shc:Shell_0773 methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; SPTR: Methylated-DNA/protein-cysteine methyltransferase; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase.
     
 0.653
ADV64331.1
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594: IPR007901; KEGG: dka:DKAM_1387 MoeB/ThiF molybdopterin or thiamine synthase protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; SPTR: MoeB/thiF molybdopterin or thiamine synthase protein; PFAM: MoeZ/MoeB domain; ThiF family.
 
   
 0.545
ADV65270.1
Molybdopterin binding domain protein; COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR001453; KEGG: dka:DKAM_0218 molybdopterin binding domain protein; PFAM: molybdopterin binding domain; SPTR: Molybdopterin binding domain protein; PFAM: Probable molybdopterin binding domain.
 
 
 0.540
ADV64332.1
thiamineS protein; InterPro IPR003749; KEGG: dka:DKAM_1388 molybdopterin converting factor, small subunit; PFAM: thiamineS protein; SPTR: Molybdopterin converting factor, small subunit; PFAM: ThiS family.
  
  
 0.536
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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