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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfdAPrefoldin, alpha subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. (153 aa)    
Predicted Functional Partners:
pfdB
Prefoldin, beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
  
 0.999
rpl31e
COGs: COG2097 Ribosomal protein L31E; InterPro IPR020052: IPR000054; KEGG: dka:DKAM_1111 50S ribosomal protein L31e; PFAM: Ribosomal protein L31e; SPTR: 50S ribosomal protein L31e; PFAM: Ribosomal protein L31e; Belongs to the ribosomal protein L31e family.
  
    0.902
rpl18a
COGs: COG2157 Ribosomal protein L20A (L18A); InterPro IPR002768; KEGG: dka:DKAM_1109 50S ribosomal protein LX; SPTR: 50S ribosomal protein LX; PFAM: Ribosomal L18ae/LX protein domain.
  
    0.899
ADV65421.1
COGs: COG2118 DNA-binding protein; InterPro IPR002836; KEGG: dka:DKAM_1113 DNA-binding TFAR19-related protein; PFAM: DNA-binding TFAR19-related protein; SPTR: DNA-binding TFAR19-related protein; PFAM: Double-stranded DNA-binding domain; Belongs to the PDCD5 family.
  
   0.899
eif6
Translation initiation factor 6 (aeIF-6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
     
 0.892
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
       0.879
rpl10
LSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
  
 0.873
rpl1
LSU ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release.
  
    0.872
rpl11
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
  
    0.870
ADV65414.1
KEGG: dka:DKAM_1106 preprotein translocase SecE subunit; SPTR: Preprotein translocase SecE subunit.
  
    0.856
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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