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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65429.1Anaerobic ribonucleoside-triphosphate reductase activating protein; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR012840: IPR007197; KEGG: dka:DKAM_1119 anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM domain protein; SPTR: Anaerobic ribonucleoside-triphosphate reductase activating protein; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM superfamily; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein. (248 aa)    
Predicted Functional Partners:
ADV65426.1
COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR012833; KEGG: tag:Tagg_0925 anaerobic ribonucleoside-triphosphate reductase; SPTR: Anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase.
 
  
 0.914
thyX
Thymidylate synthase (FAD); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
     
 0.870
ADV64621.1
COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670; KEGG: dka:DKAM_0127 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Iron-containing alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase.
 
  
 0.729
ADV65428.1
KEGG: dka:DKAM_0701 protein of unknown function (DUF996); SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF996).
       0.541
ADV65346.1
Nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: dka:DKAM_1444 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; PFAM: Aldehyde dehydrogenase family.
  
  
 0.430
ADV65432.1
KEGG: dka:DKAM_1131 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.400
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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