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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65480.1COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; InterPro IPR002500; KEGG: dka:DKAM_1179 phosphoadenosine phosphosulfate reductase; PFAM: phosphoadenosine phosphosulfate reductase; SPTR: Phosphoadenosine phosphosulfate reductase; PFAM: Phosphoadenosine phosphosulfate reductase family. (670 aa)    
Predicted Functional Partners:
ADV64434.1
COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; InterPro IPR002500; KEGG: dka:DKAM_0974 phosphoadenosine phosphosulfate reductase; PFAM: phosphoadenosine phosphosulfate reductase; SPTR: Phosphoadenosine phosphosulfate reductase; PFAM: Phosphoadenosine phosphosulfate reductase family.
  
  
 
0.922
ADV65272.1
Binding-protein-dependent transport systems inner membrane component; COGs: COG4149 ABC-type molybdate transport system permease component; InterPro IPR000515; KEGG: dka:DKAM_0216 molybdate ABC transporter, permease protein ModB; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Molybdate ABC transporter, permease protein ModB; PFAM: Binding-protein-dependent transport system inner membrane component.
 
  
 0.779
ADV64952.1
COGs: COG0031 Cysteine synthase; InterPro IPR001216: IPR001926; KEGG: tag:Tagg_1314 pyridoxal-5'-phosphate-dependent protein subunit beta; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme.
  
  
 0.541
ADV65088.1
COGs: COG0031 Cysteine synthase; InterPro IPR001216: IPR001926; KEGG: dka:DKAM_0378 pyridoxal-5'-phosphate-dependent enzyme, beta subunit; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme.
  
  
 0.541
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
     
 0.532
ADV65662.1
ABC transporter related protein; COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: tpe:Tpen_0014 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter.
 
  
 0.513
rpl3
LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
 
   
 0.503
ADV65479.1
Protein of unknown function DUF171; COGs: COG2106 conserved hypothetical protein; InterPro IPR003750; KEGG: dka:DKAM_1178 DUF171 domain containing protein; PFAM: protein of unknown function DUF171; SPTR: DUF171 domain containing protein; PFAM: Uncharacterized ACR, COG2106.
       0.486
rpl4
LSU ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
  
 
 0.477
ADV65001.1
Putative aconitase subunit 1; COGs: COG1679 conserved hypothetical protein; InterPro IPR007506; KEGG: dka:DKAM_0143 putative aconitase subunit 1; PFAM: protein of unknown function DUF521; SPTR: Putative aconitase subunit 1; PFAM: Protein of unknown function (DUF521).
  
     0.428
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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