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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
hisSCOGs: COG0124 Histidyl-tRNA synthetase; InterProIPR015807: IPR004516: IPR002314: IPR004154: IPR 006195; KEGG: dka:DKAM_1211 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; PRIAM: Histidine--tRNA ligase; SPTR: Histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (434 aa)    
Predicted Functional Partners:
ADV64368.1
COGs: COG1093 Translation initiation factor 2 alpha subunit (eIF-2alpha); InterPro IPR003029: IPR011488; KEGG: dka:DKAM_1424 translation initiation factor IF-2 subunit alpha; PFAM: translation initiation factor 2, alpha subunit; RNA binding S1 domain protein; SPTR: Translation initiation factor IF-2 subunit alpha; PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain.
   
 0.967
ADV65633.1
COGs: COG5257 Translation initiation factor 2 gamma subunit (eIF-2gamma; GTPase); InterPro IPR000795: IPR015256: IPR005225; KEGG: dka:DKAM_1347 translation initiation factor IF-2 subunit gamma; PFAM: protein synthesis factor GTP-binding; Initiation factor eIF2 gamma domain protein; SPTR: Translation initiation factor IF-2 subunit gamma; TIGRFAM: small GTP-binding protein; PFAM: Elongation factor Tu GTP binding domain; Initiation factor eIF2 gamma, C terminal; TIGRFAM: small GTP-binding protein domain; translation elongation factor TU; translation initiation factor 2 subunit gamma.
  
 0.958
thrS
COGs: COG0441 Threonyl-tRNA synthetase; InterProIPR018158: IPR002320: IPR015011: IPR002314: IPR 004154: IPR006195; KEGG: dka:DKAM_1216 threonyl-tRNA synthetase; PFAM: Threonyl-tRNA synthetase editing domain-containing protein; tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; SPTR: Threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); Archaea-specific editing domain of threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA [...]
 
 
 0.934
ADV64876.1
COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR017926: IPR006220: IPR011702: IPR004739: IPR 001674: IPR000991; KEGG: dka:DKAM_0479 GMP synthase; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; SPTR: GMP synthase; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase C terminal domain; Glutamine amidotransferase class-I; NAD synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit.
  
  
 0.898
ADV65496.1
InterPro IPR006678: IPR006677; KEGG: dka:DKAM_1212 tRNA intron endonuclease, catalytic-like protein; PFAM: tRNA intron endonuclease, catalytic domain-containing protein; tRNA intron endonuclease domain-containing protein; SPTR: tRNA intron endonuclease, catalytic-like protein; PFAM: tRNA intron endonuclease, catalytic C-terminal domain.
       0.881
cysS
COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR002308: IPR015803: IPR015273; KEGG: dka:DKAM_0804 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; PRIAM: Cysteine--tRNA ligase; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase.
 
 
 0.876
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
  
 
 0.855
ADV65267.1
COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; InterPro IPR004529: IPR002319: IPR006195; KEGG: dka:DKAM_0237 phenylalanyl-tRNA synthetase subunit alpha; PFAM: phenylalanyl-tRNA synthetase class IIc; SPTR: PheS; phenylalanyl-tRNA synthetase subunit alpha; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: tRNA synthetases class II core domain (F); TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit.
 
  
 0.847
rpl2
LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
 
 
 0.840
ADV65367.1
COGs: COG0525 Valyl-tRNA synthetase; InterPro IPR019754: IPR002300: IPR013155: IPR004039; KEGG: dka:DKAM_1053 valyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ia; tRNA synthetase valyl/leucyl anticodon-binding; SPTR: Valyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain.
  
 
 0.839
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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