close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65525.1Protein of unknown function DUF367; COGs: COG2042 conserved hypothetical protein; InterPro IPR007177; KEGG: dka:DKAM_1235 hypothetical protein; PFAM: protein of unknown function DUF367; SPTR: DUF367 containing protein; PFAM: Domain of unknown function (DUF367). (173 aa)    
Predicted Functional Partners:
ADV65526.1
InterPro IPR019887; KEGG: dka:DKAM_1236 putative transcriptional regulator, AsnC family; PFAM: Transcription regulator AsnC-type-like; SPTR: Putative transcriptional regulator, AsnC family; PFAM: AsnC family.
       0.658
rps2
COGs: COG0052 Ribosomal protein S2; InterPro IPR001865: IPR005707: IPR018130; KEGG: dka:DKAM_1358 30S ribosomal protein S2; PFAM: ribosomal protein S2; SPTR: 30S ribosomal protein S2P; TIGRFAM: ribosomal protein S2; PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein Sa(cytosolic)/S2(archaeal); Belongs to the universal ribosomal protein uS2 family.
 
    0.622
ADV64328.1
Adenylate kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily.
  
  
 0.570
rps3ae
COGs: COG1890 Ribosomal protein S3AE; InterPro IPR001593: IPR018281; KEGG: dka:DKAM_1335 30S ribosomal protein S3Ae; PFAM: ribosomal protein S3Ae; SPTR: 30S ribosomal protein S3Ae; PFAM: Ribosomal S3Ae family; Belongs to the eukaryotic ribosomal protein eS1 family.
 
    0.569
ADV64512.1
COGs: COG0478 RIO-like serine/threonine protein kinase fused to N-terminal HTH domain; InterProIPR008266: IPR018935: IPR000687: IPR015285: IPR 018934; KEGG: dka:DKAM_0022 RIO-like serine/threonine kinase; PFAM: RIO-like kinase; RIO2 kinase, winged helix domain protein; PRIAM: Non-specific serine/threonine protein kinase; SMART: protein of unknown function RIO1; SPTR: RIO-like serine/threonine kinase; PFAM: RIO1 family; Rio2, N-terminal.
 
  
 0.516
ADV65566.1
Small GTP-binding protein; COGs: COG1084 GTPase; InterPro IPR002917: IPR006073: IPR005225; KEGG: dka:DKAM_1284 small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; SPTR: Small GTP-binding protein; TIGRFAM: small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: small GTP-binding protein domain.
 
    0.506
rpl4
LSU ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
  
    0.504
rps12
SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
   
    0.493
eif6
Translation initiation factor 6 (aeIF-6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
  
  
 0.487
rpl15e
COGs: COG1632 Ribosomal protein L15E; InterPro IPR020926: IPR000439: IPR020925; KEGG: dka:DKAM_1331 50S ribosomal protein L15e; PFAM: Ribosomal protein L15e; SPTR: 50S ribosomal protein L15e; PFAM: Ribosomal L15; Belongs to the eukaryotic ribosomal protein eL15 family.
  
    0.471
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
Server load: low (28%) [HD]