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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADV65579.1DNA polymerase beta domain protein region; COGs: COG2413 nucleotidyltransferase; InterPro IPR002934: IPR009185; KEGG: dka:DKAM_1297 DNA polymerase, beta domain protein region; PFAM: DNA polymerase beta domain protein region; SPTR: DNA polymerase, beta domain protein region; PFAM: Nucleotidyltransferase domain. (239 aa)    
Predicted Functional Partners:
ADV65580.1
Peptidase M50; InterPro IPR001478: IPR008915: IPR001193; KEGG: dka:DKAM_1298 peptidase M50; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Peptidase M50; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF).
       0.712
ADV64941.1
COGs: COG2248 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR014426; KEGG: dka:DKAM_0442 predicted hydrolase (metallo-beta-lactamase superfamily); SPTR: Predicted hydrolase (Metallo-beta-lactamase superfamily); Belongs to the UPF0282 family.
  
     0.588
ADV65632.1
SSU processome protein Utp24; COGs: COG1412 Uncharacterized protein of PilT N-term./Vapc superfamily; InterPro IPR006596: IPR006984; KEGG: dka:DKAM_1346 predicted nucleic acid-binding protein, containing PIN domain; PFAM: protein of unknown function DUF652; SMART: Nucleotide binding protein PINc; SPTR: Predicted nucleic acid-binding protein, containing PIN domain; PFAM: Fcf1.
 
     0.549
ADV65545.1
COGs: COG1938 protein of ATP-grasp superfamily; KEGG: dka:DKAM_1257 ATP-grasp superfamily protein; SPTR: Archaeal enzymes of ATP-grasp superfamily; PFAM: PAC2 family.
  
     0.526
ADV65392.1
KEGG: tag:Tagg_0983 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.514
ADV65152.1
KEGG: dka:DKAM_0188 aminopeptidases-like protein; SPTR: Aminopeptidases-like protein; PFAM: Peptidase family M28.
  
     0.469
nep1
Suppressor Mra1 family protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
  
     0.469
ADV64506.1
COGs: COG1938 protein of ATP-grasp superfamily; KEGG: tag:Tagg_0179 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: PAC2 family.
  
     0.461
ADV64524.1
Radical SAM domain protein; COGs: COG2516 Biotin synthase-related protein; InterPro IPR006638: IPR007197; KEGG: dka:DKAM_0076 biotin synthase related protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Biotin synthase related protein.
 
     0.416
ADV65530.1
Protein of unknown function DUF1512; COGs: COG4046 conserved hypothetical protein; InterPro IPR009995; KEGG: dka:DKAM_1240 DUF1512 domain containing protein; PFAM: protein of unknown function DUF1512; SPTR: DUF1512 domain containing protein; PFAM: Protein of unknown function (DUF1512).
  
     0.412
Your Current Organism:
Desulfurococcus mucosus
NCBI taxonomy Id: 765177
Other names: D. mucosus DSM 2162, Desulfurococcus mucosus DSM 2162, Desulfurococcus mucosus JCM 9187, Desulfurococcus mucosus str. DSM 2162, Desulfurococcus mucosus strain DSM 2162
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