| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OSCT_0747 | OSCT_1783 | OSCT_0747 | OSCT_1783 | Serine/threonine protein kinase. | Hypothetical protein. | 0.866 |
| OSCT_0747 | OSCT_1798 | OSCT_0747 | OSCT_1798 | Serine/threonine protein kinase. | Molecular chaperone-like protein. | 0.866 |
| OSCT_0747 | clpP | OSCT_0747 | OSCT_0671 | Serine/threonine protein kinase. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.511 |
| OSCT_0747 | clpP-2 | OSCT_0747 | OSCT_1642 | Serine/threonine protein kinase. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.511 |
| OSCT_0747 | dnaK | OSCT_0747 | OSCT_0149 | Serine/threonine protein kinase. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.866 |
| OSCT_0747 | dnaK-2 | OSCT_0747 | OSCT_3214 | Serine/threonine protein kinase. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.866 |
| OSCT_0747 | groL | OSCT_0747 | OSCT_1265 | Serine/threonine protein kinase. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.819 |
| OSCT_0747 | grpE | OSCT_0747 | OSCT_0150 | Serine/threonine protein kinase. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.904 |
| OSCT_0747 | hrcA | OSCT_0747 | OSCT_0151 | Serine/threonine protein kinase. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.708 |
| OSCT_1783 | OSCT_0747 | OSCT_1783 | OSCT_0747 | Hypothetical protein. | Serine/threonine protein kinase. | 0.866 |
| OSCT_1783 | clpP | OSCT_1783 | OSCT_0671 | Hypothetical protein. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.530 |
| OSCT_1783 | clpP-2 | OSCT_1783 | OSCT_1642 | Hypothetical protein. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.530 |
| OSCT_1783 | dnaJ | OSCT_1783 | OSCT_0148 | Hypothetical protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.842 |
| OSCT_1783 | groL | OSCT_1783 | OSCT_1265 | Hypothetical protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.906 |
| OSCT_1783 | grpE | OSCT_1783 | OSCT_0150 | Hypothetical protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.971 |
| OSCT_1783 | hrcA | OSCT_1783 | OSCT_0151 | Hypothetical protein. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.813 |
| OSCT_1798 | OSCT_0747 | OSCT_1798 | OSCT_0747 | Molecular chaperone-like protein. | Serine/threonine protein kinase. | 0.866 |
| OSCT_1798 | clpP | OSCT_1798 | OSCT_0671 | Molecular chaperone-like protein. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.530 |
| OSCT_1798 | clpP-2 | OSCT_1798 | OSCT_1642 | Molecular chaperone-like protein. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.530 |
| OSCT_1798 | dnaJ | OSCT_1798 | OSCT_0148 | Molecular chaperone-like protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.937 |
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