| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OSCT_0352 | OSCT_0613 | OSCT_0352 | OSCT_0613 | Acetolactate synthase, small subunit. | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | 0.569 |
| OSCT_0352 | OSCT_0837 | OSCT_0352 | OSCT_0837 | Acetolactate synthase, small subunit. | Phosphoserine phosphatase SerB:HAD-superfamily hydrolase, subfamily IB (PSPase-like). | 0.525 |
| OSCT_0352 | OSCT_1593 | OSCT_0352 | OSCT_1593 | Acetolactate synthase, small subunit. | Threonine dehydratase. | 0.967 |
| OSCT_0352 | OSCT_1666 | OSCT_0352 | OSCT_1666 | Acetolactate synthase, small subunit. | Hypothetical protein. | 0.743 |
| OSCT_0352 | OSCT_2365 | OSCT_0352 | OSCT_2365 | Acetolactate synthase, small subunit. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.881 |
| OSCT_0352 | OSCT_2720 | OSCT_0352 | OSCT_2720 | Acetolactate synthase, small subunit. | Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | 0.922 |
| OSCT_0352 | OSCT_2969 | OSCT_0352 | OSCT_2969 | Acetolactate synthase, small subunit. | Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | 0.881 |
| OSCT_0352 | serC | OSCT_0352 | OSCT_3099 | Acetolactate synthase, small subunit. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.409 |
| OSCT_0613 | OSCT_0352 | OSCT_0613 | OSCT_0352 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | Acetolactate synthase, small subunit. | 0.569 |
| OSCT_0613 | OSCT_0614 | OSCT_0613 | OSCT_0614 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | Beta-lactamase domain-containing protein; Belongs to the UPF0173 family. | 0.774 |
| OSCT_0613 | OSCT_0837 | OSCT_0613 | OSCT_0837 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | Phosphoserine phosphatase SerB:HAD-superfamily hydrolase, subfamily IB (PSPase-like). | 0.630 |
| OSCT_0613 | OSCT_1593 | OSCT_0613 | OSCT_1593 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | Threonine dehydratase. | 0.812 |
| OSCT_0613 | OSCT_1666 | OSCT_0613 | OSCT_1666 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | Hypothetical protein. | 0.751 |
| OSCT_0613 | OSCT_2365 | OSCT_0613 | OSCT_2365 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.568 |
| OSCT_0613 | OSCT_2720 | OSCT_0613 | OSCT_2720 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | 0.895 |
| OSCT_0613 | OSCT_2969 | OSCT_0613 | OSCT_2969 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. | 0.810 |
| OSCT_0613 | glyA | OSCT_0613 | OSCT_0612 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.770 |
| OSCT_0613 | serC | OSCT_0613 | OSCT_3099 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.900 |
| OSCT_0614 | OSCT_0613 | OSCT_0614 | OSCT_0613 | Beta-lactamase domain-containing protein; Belongs to the UPF0173 family. | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | 0.774 |
| OSCT_0614 | glyA | OSCT_0614 | OSCT_0612 | Beta-lactamase domain-containing protein; Belongs to the UPF0173 family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.636 |