| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OSCT_0743 | OSCT_0906 | OSCT_0743 | OSCT_0906 | Aspartate kinase; Belongs to the aspartokinase family. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.916 |
| OSCT_0743 | OSCT_1537 | OSCT_0743 | OSCT_1537 | Aspartate kinase; Belongs to the aspartokinase family. | Homoserine dehydrogenase. | 0.998 |
| OSCT_0743 | OSCT_1593 | OSCT_0743 | OSCT_1593 | Aspartate kinase; Belongs to the aspartokinase family. | Threonine dehydratase. | 0.893 |
| OSCT_0743 | OSCT_2001 | OSCT_0743 | OSCT_2001 | Aspartate kinase; Belongs to the aspartokinase family. | Aminoglycoside phosphotransferase. | 0.558 |
| OSCT_0743 | ilvA | OSCT_0743 | OSCT_1947 | Aspartate kinase; Belongs to the aspartokinase family. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.547 |
| OSCT_0743 | proB | OSCT_0743 | OSCT_2706 | Aspartate kinase; Belongs to the aspartokinase family. | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.406 |
| OSCT_0905 | OSCT_0906 | OSCT_0905 | OSCT_0906 | (Uracil-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.783 |
| OSCT_0905 | OSCT_0907 | OSCT_0905 | OSCT_0907 | (Uracil-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | TPR repeat-containing protein. | 0.776 |
| OSCT_0906 | OSCT_0743 | OSCT_0906 | OSCT_0743 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Aspartate kinase; Belongs to the aspartokinase family. | 0.916 |
| OSCT_0906 | OSCT_0905 | OSCT_0906 | OSCT_0905 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | (Uracil-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.783 |
| OSCT_0906 | OSCT_0907 | OSCT_0906 | OSCT_0907 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | TPR repeat-containing protein. | 0.773 |
| OSCT_0906 | OSCT_1537 | OSCT_0906 | OSCT_1537 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Homoserine dehydrogenase. | 0.974 |
| OSCT_0906 | OSCT_1593 | OSCT_0906 | OSCT_1593 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Threonine dehydratase. | 0.958 |
| OSCT_0906 | OSCT_2001 | OSCT_0906 | OSCT_2001 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Aminoglycoside phosphotransferase. | 0.930 |
| OSCT_0906 | OSCT_2617 | OSCT_0906 | OSCT_2617 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Threonine aldolase. | 0.866 |
| OSCT_0906 | ilvA | OSCT_0906 | OSCT_1947 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.930 |
| OSCT_0906 | proB | OSCT_0906 | OSCT_2706 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.740 |
| OSCT_0906 | serC | OSCT_0906 | OSCT_3099 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.907 |
| OSCT_0907 | OSCT_0905 | OSCT_0907 | OSCT_0905 | TPR repeat-containing protein. | (Uracil-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.776 |
| OSCT_0907 | OSCT_0906 | OSCT_0907 | OSCT_0906 | TPR repeat-containing protein. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.773 |