| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OSCT_0405 | guaA | OSCT_0405 | OSCT_1004 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.870 |
| OSCT_0405 | ndk | OSCT_0405 | OSCT_2806 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.865 |
| OSCT_0405 | pyrG | OSCT_0405 | OSCT_1052 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.902 |
| OSCT_0405 | rpoB | OSCT_0405 | OSCT_2953 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.472 |
| argS | guaA | OSCT_2217 | OSCT_1004 | arginyl-tRNA synthetase. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.975 |
| argS | guaB | OSCT_2217 | OSCT_2120 | arginyl-tRNA synthetase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.461 |
| argS | pnp | OSCT_2217 | OSCT_1127 | arginyl-tRNA synthetase. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.641 |
| argS | pyrG | OSCT_2217 | OSCT_1052 | arginyl-tRNA synthetase. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.885 |
| argS | rho | OSCT_2217 | OSCT_0228 | arginyl-tRNA synthetase. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.479 |
| argS | rpoB | OSCT_2217 | OSCT_2953 | arginyl-tRNA synthetase. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.662 |
| argS | rpsB | OSCT_2217 | OSCT_1572 | arginyl-tRNA synthetase. | Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.570 |
| guaA | OSCT_0405 | OSCT_1004 | OSCT_0405 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent. | 0.870 |
| guaA | argS | OSCT_1004 | OSCT_2217 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | arginyl-tRNA synthetase. | 0.975 |
| guaA | guaB | OSCT_1004 | OSCT_2120 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
| guaA | ndk | OSCT_1004 | OSCT_2806 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.626 |
| guaA | pnp | OSCT_1004 | OSCT_1127 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.867 |
| guaA | pyrG | OSCT_1004 | OSCT_1052 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.962 |
| guaA | rho | OSCT_1004 | OSCT_0228 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.458 |
| guaA | rplY | OSCT_1004 | OSCT_0434 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.611 |
| guaA | rpoB | OSCT_1004 | OSCT_2953 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.928 |