STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OSCT_1359uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (266 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 0.999
OSCT_1360
Porphobilinogen synthase; Belongs to the ALAD family.
 0.999
OSCT_2402
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 0.994
hemL
Glutamate-1-semialdehyde-2,1-aminomutase.
 
 
 0.978
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.969
OSCT_2408
Cobalamin (vitamin B12) biosynthesis CbiX protein.
  
 
 0.957
OSCT_2403
precorrin-3B C17-methyltransferase.
 
 
 0.956
OSCT_1361
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.937
OSCT_0978
Cytochrome c assembly protein.
  
  
 0.900
OSCT_2404
Precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family.
    
 0.893
Your Current Organism:
Oscillochloris trichoides
NCBI taxonomy Id: 765420
Other names: O. trichoides DG-6, Oscillochloris trichoides DG-6, Oscillochloris trichoides str. DG-6, Oscillochloris trichoides strain DG-6
Server load: low (36%) [HD]