| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OSCT_0978 | OSCT_1359 | OSCT_0978 | OSCT_1359 | Cytochrome c assembly protein. | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.900 |
| OSCT_0978 | OSCT_1360 | OSCT_0978 | OSCT_1360 | Cytochrome c assembly protein. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.442 |
| OSCT_0978 | OSCT_2402 | OSCT_0978 | OSCT_2402 | Cytochrome c assembly protein. | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.470 |
| OSCT_0978 | hemA | OSCT_0978 | OSCT_1357 | Cytochrome c assembly protein. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.570 |
| OSCT_0978 | hemC | OSCT_0978 | OSCT_1358 | Cytochrome c assembly protein. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.487 |
| OSCT_0978 | hemL | OSCT_0978 | OSCT_1362 | Cytochrome c assembly protein. | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.502 |
| OSCT_1359 | OSCT_0978 | OSCT_1359 | OSCT_0978 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Cytochrome c assembly protein. | 0.900 |
| OSCT_1359 | OSCT_1360 | OSCT_1359 | OSCT_1360 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.999 |
| OSCT_1359 | OSCT_1361 | OSCT_1359 | OSCT_1361 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.937 |
| OSCT_1359 | OSCT_2402 | OSCT_1359 | OSCT_2402 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.994 |
| OSCT_1359 | OSCT_2403 | OSCT_1359 | OSCT_2403 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | precorrin-3B C17-methyltransferase. | 0.956 |
| OSCT_1359 | OSCT_2404 | OSCT_1359 | OSCT_2404 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.893 |
| OSCT_1359 | OSCT_2408 | OSCT_1359 | OSCT_2408 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Cobalamin (vitamin B12) biosynthesis CbiX protein. | 0.957 |
| OSCT_1359 | hemA | OSCT_1359 | OSCT_1357 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.969 |
| OSCT_1359 | hemC | OSCT_1359 | OSCT_1358 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
| OSCT_1359 | hemL | OSCT_1359 | OSCT_1362 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.978 |
| OSCT_1360 | OSCT_0978 | OSCT_1360 | OSCT_0978 | Porphobilinogen synthase; Belongs to the ALAD family. | Cytochrome c assembly protein. | 0.442 |
| OSCT_1360 | OSCT_1359 | OSCT_1360 | OSCT_1359 | Porphobilinogen synthase; Belongs to the ALAD family. | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.999 |
| OSCT_1360 | OSCT_1361 | OSCT_1360 | OSCT_1361 | Porphobilinogen synthase; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.858 |
| OSCT_1360 | OSCT_2402 | OSCT_1360 | OSCT_2402 | Porphobilinogen synthase; Belongs to the ALAD family. | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.907 |