STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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OSCT_1553acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (644 aa)    
Predicted Functional Partners:
OSCT_2720
Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
  
 
 0.935
OSCT_1554
AMP-dependent synthetase and ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
 
  
 
0.880
OSCT_1889
Citrate synthase I; Belongs to the citrate synthase family.
  
 0.870
OSCT_1623
Malate synthase; Belongs to the malate synthase family.
   
 0.868
OSCT_2969
Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
  
 
 0.853
OSCT_0777
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.849
OSCT_1136
acetyl-CoA acetyltransferase-like protein.
  
 
 0.849
OSCT_2287
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.849
OSCT_1410
Acetyl coenzyme A synthetase subunit alpha.
    
 0.831
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 
 0.827
Your Current Organism:
Oscillochloris trichoides
NCBI taxonomy Id: 765420
Other names: O. trichoides DG-6, Oscillochloris trichoides DG-6, Oscillochloris trichoides str. DG-6, Oscillochloris trichoides strain DG-6
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