Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OSCT_1554AMP-dependent synthetase and ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (632 aa)    
Predicted Functional Partners:
OSCT_2720
Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
  
 
 0.935
OSCT_1553
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
 
  
 
0.880
OSCT_1900
Hypothetical protein.
  
 0.825
OSCT_1410
Acetyl coenzyme A synthetase subunit alpha.
    
 0.787
OSCT_2969
Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
  
 
 0.784
OSCT_3094
acetyl-CoA carboxylase, biotin carboxylase.
  
 0.781
OSCT_1498
acyl-CoA dehydrogenase domain protein.
  
 
 0.780
OSCT_0950
Dehydrogenase catalytic domain-containing protein.
  
 
 0.779
OSCT_1424
AMP-dependent synthetase and ligase.
 
0.722
OSCT_0507
Beta-ketoacyl synthase.
  
 0.642
Your Current Organism:
Oscillochloris trichoides
NCBI taxonomy Id: 765420
Other names: O. trichoides DG-6, Oscillochloris trichoides DG-6, Oscillochloris trichoides str. DG-6, Oscillochloris trichoides strain DG-6
Server load: low (16%) [HD]