| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OSCT_1359 | OSCT_1360 | OSCT_1359 | OSCT_1360 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.999 |
| OSCT_1359 | OSCT_1800 | OSCT_1359 | OSCT_1800 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen III synthase HEM4. | 0.583 |
| OSCT_1359 | OSCT_2402 | OSCT_1359 | OSCT_2402 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.997 |
| OSCT_1359 | OSCT_2403 | OSCT_1359 | OSCT_2403 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | precorrin-3B C17-methyltransferase. | 0.976 |
| OSCT_1359 | OSCT_2405 | OSCT_1359 | OSCT_2405 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit. | 0.774 |
| OSCT_1359 | hemA | OSCT_1359 | OSCT_1357 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.967 |
| OSCT_1359 | hemC | OSCT_1359 | OSCT_1358 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
| OSCT_1359 | hemL | OSCT_1359 | OSCT_1362 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.973 |
| OSCT_1360 | OSCT_1359 | OSCT_1360 | OSCT_1359 | Porphobilinogen synthase; Belongs to the ALAD family. | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.999 |
| OSCT_1360 | OSCT_1800 | OSCT_1360 | OSCT_1800 | Porphobilinogen synthase; Belongs to the ALAD family. | Uroporphyrinogen III synthase HEM4. | 0.916 |
| OSCT_1360 | OSCT_2402 | OSCT_1360 | OSCT_2402 | Porphobilinogen synthase; Belongs to the ALAD family. | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.900 |
| OSCT_1360 | OSCT_2403 | OSCT_1360 | OSCT_2403 | Porphobilinogen synthase; Belongs to the ALAD family. | precorrin-3B C17-methyltransferase. | 0.654 |
| OSCT_1360 | OSCT_2405 | OSCT_1360 | OSCT_2405 | Porphobilinogen synthase; Belongs to the ALAD family. | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit. | 0.515 |
| OSCT_1360 | hemA | OSCT_1360 | OSCT_1357 | Porphobilinogen synthase; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.936 |
| OSCT_1360 | hemC | OSCT_1360 | OSCT_1358 | Porphobilinogen synthase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
| OSCT_1360 | hemL | OSCT_1360 | OSCT_1362 | Porphobilinogen synthase; Belongs to the ALAD family. | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.998 |
| OSCT_1799 | OSCT_1800 | OSCT_1799 | OSCT_1800 | VanW family protein. | Uroporphyrinogen III synthase HEM4. | 0.516 |
| OSCT_1799 | OSCT_1801 | OSCT_1799 | OSCT_1801 | VanW family protein. | Hydroxypyruvate reductase. | 0.516 |
| OSCT_1800 | OSCT_1359 | OSCT_1800 | OSCT_1359 | Uroporphyrinogen III synthase HEM4. | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.583 |
| OSCT_1800 | OSCT_1360 | OSCT_1800 | OSCT_1360 | Uroporphyrinogen III synthase HEM4. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.916 |