Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
OSCT_2402uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (265 aa)    
Predicted Functional Partners:
OSCT_1359
uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
 0.994
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.992
OSCT_2403
precorrin-3B C17-methyltransferase.
 
 
0.987
OSCT_2404
Precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family.
  
 0.983
OSCT_2408
Cobalamin (vitamin B12) biosynthesis CbiX protein.
 
 0.969
OSCT_1800
Uroporphyrinogen III synthase HEM4.
 
 0.967
OSCT_1360
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.907
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.889
OSCT_1361
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
    
 0.836
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.790
Your Current Organism:
Oscillochloris trichoides
NCBI taxonomy Id: 765420
Other names: O. trichoides DG-6, Oscillochloris trichoides DG-6, Oscillochloris trichoides str. DG-6, Oscillochloris trichoides strain DG-6
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