| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OSCT_1304 | OSCT_1543 | OSCT_1304 | OSCT_1543 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.921 |
| OSCT_1304 | nadD | OSCT_1304 | OSCT_2485 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Methyltransferase GidB; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.935 |
| OSCT_1304 | nadE | OSCT_1304 | OSCT_0473 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.903 |
| OSCT_1304 | nadE-2 | OSCT_1304 | OSCT_2746 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.473 |
| OSCT_1543 | OSCT_1304 | OSCT_1543 | OSCT_1304 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.921 |
| OSCT_1543 | cobB | OSCT_1543 | OSCT_0396 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily. | 0.618 |
| OSCT_1543 | nadD | OSCT_1543 | OSCT_2485 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Methyltransferase GidB; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.924 |
| OSCT_1543 | nadE | OSCT_1543 | OSCT_0473 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.787 |
| OSCT_1543 | nadE-2 | OSCT_1543 | OSCT_2746 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.654 |
| OSCT_2747 | OSCT_2748 | OSCT_2747 | OSCT_2748 | Asparagine synthase (glutamine-hydrolyzing). | AMP-dependent synthetase and ligase. | 0.612 |
| OSCT_2747 | guaA | OSCT_2747 | OSCT_1004 | Asparagine synthase (glutamine-hydrolyzing). | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.449 |
| OSCT_2747 | nadE | OSCT_2747 | OSCT_0473 | Asparagine synthase (glutamine-hydrolyzing). | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.456 |
| OSCT_2747 | nadE-2 | OSCT_2747 | OSCT_2746 | Asparagine synthase (glutamine-hydrolyzing). | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.849 |
| OSCT_2748 | OSCT_2747 | OSCT_2748 | OSCT_2747 | AMP-dependent synthetase and ligase. | Asparagine synthase (glutamine-hydrolyzing). | 0.612 |
| OSCT_2748 | nadE-2 | OSCT_2748 | OSCT_2746 | AMP-dependent synthetase and ligase. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.555 |
| coaD | cobB | OSCT_0169 | OSCT_0396 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily. | 0.421 |
| coaD | guaA | OSCT_0169 | OSCT_1004 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.728 |
| coaD | nadD | OSCT_0169 | OSCT_2485 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Methyltransferase GidB; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.619 |
| coaD | nadE | OSCT_0169 | OSCT_0473 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.824 |
| coaD | nadE-2 | OSCT_0169 | OSCT_2746 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.435 |