STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa)    
Predicted Functional Partners:
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
OSCT_2946
Succinate dehydrogenase and fumarate reductase iron-sulfur protein.
  
 0.993
OSCT_2945
Succinate dehydrogenase or fumarate reductase, flavoprotein subunit.
  
 0.990
OSCT_2887
Alpha-ketoglutarate decarboxylase.
 0.987
OSCT_2886
Hypothetical protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.967
OSCT_2720
Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
  
 
 0.951
OSCT_1896
Dihydrolipoyllysine-residue succinyltransferase.
  
 0.938
OSCT_1909
NADH dehydrogenase (quinone).
  
 
 0.938
OSCT_0551
Glutamate synthase (ferredoxin).
  
 
 0.929
OSCT_2944
Succinate dehydrogenase/fumarate reductase cytochrome b subunit.
    
 0.925
Your Current Organism:
Oscillochloris trichoides
NCBI taxonomy Id: 765420
Other names: O. trichoides DG-6, Oscillochloris trichoides DG-6, Oscillochloris trichoides str. DG-6, Oscillochloris trichoides strain DG-6
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